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LNX1 antibody

Principal name

LNX1 antibody

Alternative names for LNX1 antibody

LNX, LNX-1, E3 ubiquitin-protein ligase LNX, Numb-binding protein 1, Ligand of Numb-protein X 1

SwissProt ID

O70263 (Mouse), Q8TBB1 (Human), Q8TBB1-2

Gene ID

84708 (LNX1), 16924 (Lnx1)

Ncbi ID

NP_001119800.1, NP_116011, 9606, NM_032622, NM_001159579, NM_001159578, NP_001153049.1, NM_010727, NM_001159577, NM_001126328

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection))

Background of LNX1 antibody

LNX1 is a membrane-bound protein that is involved in signal transduction and protein interactions. LNX1 is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis.This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.

General readings

Weiss,A., (2007) FEBS Lett. 581 (26), 5131-5136

Transfected 293T; WB Suggested Anti-LNX1 Antibody Titration: 1.25ug/ml. Positive Control: Transfected 293T; LNX1 antibody - C-terminal region (ARP43367_T100) in Transfected 293T cells using Western Blot

ARP43367_T100

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY LNX1 (RC206386, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-LNX1.

TA800747

WB Suggested Anti-LNX1 Antibody Titration: 1.25 ug/ml; Positive Control: Transfected 293T

TA330487

Primary Antibodies

Catalog No.	Host	Iso.	Clone	Pres.	React.	Applications
TA800747	LNX1 antibody
	LNX1 mouse monoclonal antibody, clone OTI1H9 (formerly 1H9)
	Mouse	IgG1	OTI1H9	Purified	Hu	WB	0.1 ml / €379.00
							OriGene Technologies, Inc.

AP05289PU-N	LNX1 antibody
	Rabbit			Aff - Purified	Hu	WB	0.1 mg / €400.00
							OriGene Technologies GmbH
AP05289SU-N	LNX1 antibody
	Rabbit			Purified	Hu	WB	0.1 mg / €400.00
							OriGene Technologies GmbH

Lysates

Catalog No.
LY403178	LNX1 overexpression lysate
		0.1 mg / €295.00
		OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.
MR219190L2V	Lenti ORF particles, Lnx1 (GFP-tagged) - Mouse ligand of numb-protein X 1 (Lnx1), transcript variant 1, 200 uL, >10^7 TU/mL
		200 µl / €1,500.00
		OriGene Technologies, Inc.

MR216086L2V	Lenti ORF particles, Lnx1 (GFP-tagged) - Mouse ligand of numb-protein X 1 (Lnx1), transcript variant 2, 200 uL, >10^7 TU/mL
		200 µl / €1,360.00
		OriGene Technologies, Inc.

MR217650L2V	Lenti ORF particles, Lnx1 (GFP-tagged) - Mouse ligand of numb-protein X 1 (Lnx1), transcript variant 3, 200 uL, >10^7 TU/mL
		200 µl / €1,280.00
		OriGene Technologies, Inc.

MR216103L2V	Lenti ORF particles, Lnx1 (GFP-tagged) - Mouse ligand of numb-protein X 1 (Lnx1), transcript variant 4, 200 uL, >10^7 TU/mL
		200 µl / €1,360.00
		OriGene Technologies, Inc.

MR219190L1V	Lenti ORF particles, Lnx1 (Myc-DDK-tagged) - Mouse ligand of numb-protein X 1 (Lnx1), transcript variant 1, 200 uL, >10^7 TU/mL
		200 µl / €1,350.00
		OriGene Technologies, Inc.

MR216086L1V	Lenti ORF particles, Lnx1 (Myc-DDK-tagged) - Mouse ligand of numb-protein X 1 (Lnx1), transcript variant 2, 200 uL, >10^7 TU/mL
		200 µl / €1,220.00
		OriGene Technologies, Inc.

MR216103L1V	Lenti ORF particles, Lnx1 (Myc-DDK-tagged) - Mouse ligand of numb-protein X 1 (Lnx1), transcript variant 4, 200 uL, >10^7 TU/mL
		200 µl / €1,220.00
		OriGene Technologies, Inc.

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