LRRC1 antibody
Principal name
LRRC1 antibody
Alternative names for LRRC1 antibody
LRRC1, LANO, Leucine-rich repeat-containing protein 1, LAP and no PDZ protein, LANO adapter protein
SwissProt ID
Q9BTT6 (Human)
Gene ID
55227 (LRRC1)
Ncbi ID
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)
Background of LRRC1 antibody
Lano is a member of the LAP (leucine-rich repeats and PDZ) family of proteins that also includes Densin-180, Erbin, and hScribble. The LAP family of proteins is involved in the regulation of cell adhesion, cell shape and polarity. The LAP proteins generally contain multiple leucine-rich repeat (LRR) domains which serve to target them to the basolateral membrane of epithelial cells. Lano is unique in that it alone does not possess one or more PDZ domains as do the other members of the LAP family. However, it can bind to the PDZ domain of Erbin in addition to those of membrane-associated and guanylate kinase (MAGUK) proteins which regulate adhesion and plasticity at cell junctions. It has been suggested that it is through these interaction that these LAP proteins participate in the maintenance of proper embryonic development and integrity of epithelial tissues.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA306094 | LRRC1 antibody |
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| Rabbit Polyclonal Lano Antibody | |||||||
 |
Rabbit | IgG | Aff - Purified | Hu | E, P, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
|||||||
| AP07768PU-N | LRRC1 (C-term) antibody |
||||||
 |
Rabbit | Aff - Purified | Hu | P, WB |
50 µg /
€425.00
|
||
| OriGene Technologies GmbH | |||||||
| +1 additional image |
|||||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY413222 | LRRC1 overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
