MAP4K2 antibody
Principal name
MAP4K2 antibody
Alternative names for MAP4K2 antibody
MAPK, MEK kinase kinase 2, MEKKK 2, RAB8IP, Germinal center kinase, B lymphocyte serine/threonine-protein kinase, Rab8-interacting protein, Mitogen-activated protein kinase kinase kinase kinase 2
Ncbi ID
9606, 5874, NP_004570, NP_004570.2, NP_033032.1, NM_009006, NM_004579
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Flow Cytometry (F)
Background of MAP4K2 antibody
MAP4K2 is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.The protein encoded by this gene is a member of the serine/threonine protein kinase family. Although this kinase is found in many tissues, its expression in lymphoid follicles is restricted to the cells of germinal centre, where it may participate in B-cell differentiation. This kinase can be activated by TNF-alpha, and has been shown to specifically activate MAP kinases. This kinase is also found to interact with TNF receptor-associated factor 2 (TRAF2), which is involved in the activation of MAP3K1/MEKK1.
General readings
Bailey, S.D., et al. Diabetes Care (2010) In press
Fidalgo, M., et al. J. Cell. Sci. 123 (PT 8), 1274-1284 (2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wissing, J., et al. Mol. Cell Proteomics 6(3):537-547(2007)
Chadee, D.N., et al. Mol. Cell. Biol. 22(3):737-749(2002)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA349584 | MAP4K2 antibody |
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| Rabbit Polyclonal Anti-MAP4K2 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| AP13626PU-N | MAP4K2 antibody |
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 |
Rabbit | Ig | Purified | Hu, Ms | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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| AP52600PU-N | MAP4K2 (Center) antibody |
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 |
Rabbit | Ig | Aff - Purified | Hu | F, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
| +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP317608 | MAP4K2 |
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| Recombinant protein of human mitogen-activated protein kinase kinase kinase kinase 2 (MAP4K2) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR217131L2V | Lenti ORF particles, Map4k2 (GFP-tagged) - Mouse mitogen-activated protein kinase kinase kinase kinase 2 (Map4k2), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€1,640.00
|
|
| OriGene Technologies, Inc. | ||
| MR217131L1V | Lenti ORF particles, Map4k2 (Myc-DDK-tagged) - Mouse mitogen-activated protein kinase kinase kinase kinase 2 (Map4k2), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,470.00
|
|
| OriGene Technologies, Inc. | ||
