MCM8 antibody
Principal name
MCM8 antibody
Alternative names for MCM8 antibody
C20orf154, minichromosome maintenance complex component 8, DNA replication licensing factor MCM8
Ncbi ID
9606, NP_115874, NP_115874.3, NP_079952.2, NM_025676, BC046780, NM_032485, NM_182802
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of MCM8 antibody
MCM8 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein contains the central domain that is conserved among the MCM proteins. This protein has been shown to co-immunoprecipitate with MCM4, 6 and 7, which suggests that it may interact with other MCM proteins and play a role in DNA replication. Alternatively spliced transcript variants encoding distinct isoforms have been described.
General readings
Volkening,M., et al., (2005) Mol. Cell. Biol. 25 (4), 1560-1568
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA322142 | MCM8 antibody |
||||||
| Anti-MCM8 Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR210873L2V | Lenti ORF particles, Mcm8 (GFP-tagged) - Mouse minichromosome maintenance deficient 8 (S, 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€1,470.00
|
|
| OriGene Technologies, Inc. | ||
| MR210756L2V | Lenti ORF particles, Mcm8 (GFP-tagged) - Mouse minichromosome maintenance deficient 8 (S. cerevisiae) (Mcm8), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,610.00
|
|
| OriGene Technologies, Inc. | ||
| MR210873L1V | Lenti ORF particles, Mcm8 (Myc-DDK-tagged) - Mouse minichromosome maintenance deficient 8 (S, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,330.00
|
|
| OriGene Technologies, Inc. | ||
| MR210756L1V | Lenti ORF particles, Mcm8 (Myc-DDK-tagged) - Mouse minichromosome maintenance deficient 8 (S. cerevisiae) (Mcm8), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,450.00
|
|
| OriGene Technologies, Inc. | ||
