MED27 antibody
Principal name
MED27 antibody
Alternative names for MED27 antibody
CRSP34, CRSP8, Mediator complex 27, CRSP complex subunit 8, Mediator of RNA polymerase II transcription subunit 27, Cofactor required for Sp1 transcriptional activation subunit 8
Ncbi ID
9606, NP_004260, NP_004260.2, NP_081172.2, BC016537, NM_026896
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection))
Background of MED27 antibody
he activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. CRSP8 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. CRSP8 is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
General readings
Malik S., et al. (2000) Mol. Cell. 5:753-760Ryu S., et al. (1999) Nature. 397:446-450
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA314912 | MED27 antibody |
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| Rabbit polyclonal anti-MED27 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR203667L2V | Lenti ORF particles, Crsp8 (GFP-tagged) - Mouse cofactor required for Sp1 transcriptional activation, subunit 8 (cDNA clone MGC:29026 IMAGE:3585027), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€1,240.00
|
|
| OriGene Technologies, Inc. | ||
| MR203667L1V | Lenti ORF particles, Crsp8 (Myc-DDK-tagged) - Mouse cofactor required for Sp1 transcriptional activation, subunit 8 (cDNA clone MGC:29026 IMAGE:3585027), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,110.00
|
|
| OriGene Technologies, Inc. | ||