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MEIS1 antibody

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Principal name

MEIS1 antibody

Alternative names for MEIS1 antibody

Homeobox protein Meis1

SwissProt ID

O00470 (Human), Q60954 (Mouse)

Gene ID

4211 (MEIS1), 17268 (Meis1)

Ncbi ID

9606, NP_002389, NP_002389.1, NP_001180200.1, NM_010789, NM_001193271

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of MEIS1 antibody

Hox, Pbx, and Meis families of transcription factors form heteromeric complexes and bind DNA through specific homeobox domains. Hox proteins are involved in regulating tissue patterning during development, and they are also expressed n lineage- and stage-specific patterns during adult ematopoietic ifferentiation and in leukemias. The Hox proteins, which include paralog groups 1 to 10, have a low intrinsic binding affinity for DNA and are instead associated into cooperative DNA binding complexes with Pbx or the Pbx related Meis proteins, which result in an enhanced Hox-DNA binding affinity and an increased selectivity for the binding site. Both Meis1 and 2 (also known as Meis-related gene 1) are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. In addition to binding with Hox proteins, Meis1 also forms heterodimers with the ubiquitously expressed Pbx proteins, including Pbx1, Pbx2 and Pbx3, and these complexes contain distinct DNA-binding specificities.

General readings

Wong P, Iwasaki M, Somervaille TC, So CW, Cleary ML.
Meis1 is an essential and rate-limiting regulator of MLL leukemia stem cell potential.
Genes Dev. 2007 Nov 1;21(21):2762-74. Epub 2007 Oct 17. Erratum in: Genes Dev.
PMID: 17942707

ARP38149_P050 - MEIS1
Human Liver; WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Liver; MEIS1 antibody - C-terminal region (ARP38149_P050) in Human Liver cells using Western Blot
PAB11460 - MEIS1
MEIS1 polyclonal antibody ( Cat # PAB11460 ) ( 0.1 µg/ml ) staining of human cerebral cortex lysate ( 35 µg protein in RIPA buffer ). Primary incubation was 1 hour. Detected by chemiluminescence.
ARP32017_P050 - MEIS1
Human Lung; WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: Human Lung; MEIS1 antibody - middle region (ARP32017_P050) in Human Lung cells using Western Blot
AP20611PU-N - MEIS1
Western blot (WB) analysis of Meis1 antibody (Cat.-No.: AP20611PU-N) in extracts from Jurkat cells.
TA590689 - MEIS1
ELISA: MEIS1 Antibody
TA305776 - MEIS1
TA305776 (0.1ug/ml) staining of Human Cerebral Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA329751 - MEIS1
WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human Lung
TA335835 - MEIS1
WB Suggested Anti-MEIS1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human Liver

7 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MEIS1 antibody
  Goat Anti-MEIS1 Antibody  
TA305776 (0.1ug/ml) staining of Human Cerebral Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

MEIS1 antibody
  Rabbit Polyclonal MEIS1 Antibody  
ELISA: MEIS1 Antibody Rabbit IgG Purified Hu E
0.1 mg / €409.00
  OriGene Technologies, Inc.

MEIS1 antibody
Western blot (WB) analysis of Meis1 antibody (Cat.-No.: AP20611PU-N) in extracts from Jurkat cells. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €370.00
  OriGene Technologies GmbH

CRISPR

Catalog No. Species Donor Vector  

Meis1 - mouse gene knockout kit via CRISPR
Meis1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Meis1 - mouse gene knockout kit via CRISPR
Meis1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Meis1 - mouse gene knockout kit via CRISPR
Meis1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Meis1 - mouse gene knockout kit via CRISPR
Meis1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

7 Item(s)

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Available Filters

Product Type
  1. CRISPR (4)
  2. Primary Antibody (3)
Clonality
  1. Polyclonal (3)
Target
  1. MEIS1 (3)
Reactivity
  1. Human (Hu) (3)
  2. Mouse (Ms) (2)
  3. Bovine (Bov) (1)
  4. Rat (Rt) (1)
Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Enzyme Immunoassay (E) (1)
Presentation
  1. Aff - Purified (2)
  2. Purified (1)
Host
  1. Rabbit (2)
  2. Goat (1)
Images
  1. 1 image (3)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Enzyme Immunoassay (E) (1)
Species (CRISPR)
  1. Mouse (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. OriGene Technologies (7)
Service
  • OriGene Technologies GmbH
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  • Germany
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