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METAP2 antibody

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Principal name

METAP2 antibody

Alternative names for METAP2 antibody

Methionine aminopeptidase 2, MetAP 2, MAP 2, MNPEP, P67EIF2, Peptidase M 2, p67eIF2, Initiation factor 2-associated 67 kDa glycoprotein

SwissProt ID

O08663 (Mouse), P38062 (Rat), P38174 (Yeast), P50579 (Human), Q3ZC89 (Bovin)

Gene ID

10988 (METAP2), 56307 (Metap2), 64370

Ncbi ID

9606, NP_006829, 5874, NP_006829.1, NM_006838, NP_062622.1, NM_019648, NM_022539

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat), Ze (Zebrafish), African clawed frog, Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of METAP2 antibody

METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site.This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Kass,D., (2007) Am. J. Respir. Cell Mol. Biol. 37 (2), 193-201

PAB4290 - METAP2
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with METAP2 polyclonal antibody ( Cat # PAB4290 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining . This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated .
ARP52266_P050 - METAP2
Human Jurkat; Host: Rabbit . Target Name: METAP2 . Sample Tissue: Jurkat . Antibody Dilution: 1.0ug/ml. METAP2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells.; METAP2 antibody - N-terminal region (ARP52266_P050) in Human Jurkat cells using Western Blot
ARP52266_P050 - METAP2
Human brain; WB Suggested Anti-METAP2 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human brain; METAP2 antibody - N-terminal region (ARP52266_P050) in Human brain cells using Western Blot
AP12162PU-N - METAP2
Western blot analysis of METAP2 Antibody (N-term) (Cat.#AP12162PU-N) in 293 cell line lysates (35 µg/lane). METAP2 (arrow) was detected using the purified Pab.
AP12163PU-N - METAP2
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with METAP2 antibody (C-term) (Cat#AP12163PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
AP12163PU-N - METAP2
Western blot analysis of METAP2 Antibody (C-term) (Cat.#AP2320b) in 293 cell line lysates (35 µg/lane). METAP2 (arrow) was detected using the purified Pab.
H00010988-B01P - METAP2
Immunofluorescence of purified MaxPab antibody to METAP2 on HeLa cell. [antibody concentration 10 ug/ml]
H00010988-B01P - METAP2
METAP2 MaxPab polyclonal antibody. Western Blot analysis of METAP2 expression in human liver.
H00010988-B01P - METAP2
Western Blot analysis of METAP2 expression in transfected 293T cell line (H00010988-T02) by METAP2 MaxPab polyclonal antibody.Lane 1: METAP2 transfected lysate(52.58 KDa).Lane 2: Non-transfected lysate.
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Human breast tissue within the normal limits using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Human pancreas tissue within the normal limits using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289)
TA800289 - METAP2
Anti-METAP2 mouse monoclonal antibody (TA800289) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY METAP2(RC203809).
TA800289 - METAP2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY METAP2 (RC203809, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-METAP2.
TA800289 - METAP2
HEK293T cells transfected with either RC203809 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-METAP2 antibody(TA800289), and then analyzed by flow cytometry.
TA340142 - METAP2
WB Suggested Anti-METAP2 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human brain
TA340142 - METAP2
Host: Rabbit; Target Name: METAP2; Sample Tissue: Jurkat; Antibody Dilution: 1.0 ug/mlMETAP2 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

METAP2 antibody
  METAP2 (Methionine Aminopeptidase 2) mouse monoclonal antibody, clone OTI1F6 (formerly 1F6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-METAP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA800289) Mouse IgG1 OTI1F6 Purified Hu F, ICC/IF, P, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.
+10 additional images

Highly validated antibody!

TrueMAB

METAP2 (N-term) antibody
Western blot analysis of METAP2 Antibody (N-term) (Cat.#AP12162PU-N) in 293 cell line lysates (35 µg/lane). METAP2 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu
0.4 ml / €415.00
  OriGene Technologies GmbH

METAP2 (C-term) antibody
Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with METAP2 antibody (C-term) (Cat#AP12163PU-N), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Purified Hu P
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.    

METAP2 overexpression lysate
METAP2 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Metap2 (GFP-tagged) - Mouse methionine aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Metap2 (GFP-tagged) - Mouse methionine aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Metap2 (Myc-DDK-tagged) - Mouse methionine aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Metap2 (Myc-DDK-tagged) - Mouse methionine aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL  
200 µl / €1,030.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Metap2 (GFP-tagged ORF) - Rat methionyl aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Metap2 (GFP-tagged ORF) - Rat methionyl aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL  
200 µl / €1,160.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Metap2 (Myc-DDK-tagged ORF) - Rat methionyl aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL
Lenti ORF particles, Metap2 (Myc-DDK-tagged ORF) - Rat methionyl aminopeptidase 2 (Metap2), 200 uL, >10^7 TU/mL  
200 µl / €1,040.00
  OriGene Technologies, Inc.
 

8 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Mouse Lenti ORF Particle (2)
  3. Primary Antibody (3)
  4. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (2)
  2. Monoclonal (1)
Target
  1. METAP2 (3)
Property
  1. C-term (1)
  2. N-term (1)
Reactivity
  1. Human (Hu) (3)
Applications
  1. Paraffin Sections (P) (2)
  2. Flow cytometry (F) (1)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  4. Western blot / Immunoblot (WB) (1)
Presentation
  1. Purified (3)
Host
  1. Rabbit (2)
  2. Mouse (1)
Images
  1. 1 image (3)
  2. 3+ images (1)
  3. 5+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Paraffin Sections (P) (2)
  3. Flow cytometry (F) (1)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Manufacturer
  1. OriGene Technologies (8)
Service
  • OriGene Technologies GmbH
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