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MHC Class I antibody

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Principal name

MHC Class I antibody

Alternative names for MHC Class I antibody

MHC Class 1, HLA Class 1, Major Histocompatibility complex class I

Available reactivities

Rb (Rabbit), Eq (Equine), Sh (Sheep), Bov (Bovine), GP (Guinea Pig), Hst (Hamster), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Chk (Chicken), Av (Birds)

Available hosts

Mouse, Rat

Available applications

Flow Cytometry (F), Immunoprecipitation (IP), Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of MHC Class I antibody

MHC Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. MHC class I antigens are heterodimers consisting of one alpha chain (44kDa) with beta 2 microglobulin (11.5 kDa). The antigen is expressed by all somatic cells at varying levels. MHC Class I molecules are expressed on most nucleated cells where they present endogenously synthesized antigenic peptides to CD8+ T lymphocytes, which are usually cytotoxic T cells. (Ref.1-3) Fibroblasts or neurons however only show a low level of antigen.

General readings

1. Gogolin-Ewens, K. et al. (1985) Sheep lymphocyte antigens (OLA). Immunology. 56:
717 - 723.
2. Puri, N. et al. (1987) Monoclonal antibodies to sheep MHC class I and class II molecules: Biochemical characterization of three class I gene products and four distinct subpopulations of class II molecules. Vet. Immunol. Immunopathol. 15: 59 - 86.

SM504 - MHC Class I
Staining of equine peripheral blood lymphocytes with MOUSE ANTI EQUINE MHC Class 1 (SM504), visualised with RABBIT ANTI MOUSE IgG:FITC (SP1012F).
AM08130FC-N - MHC Class I
Immunofluorescent Staining: Chicken peripheral blood mononuclear cells were double-stained with Mouse anti-Chicken MHC Class I-FITC and Mouse anti-Chicken IgM-PE. Small lymphocytes were then gated and analyzed on a FACScan(TM) flow cytometer (BDIS, San Jose, CA). Amount Used: 1 µg/10e6 cells.
NBP1-28304 - MHC Class I
Flow cytometry / FACS analysis: MHC Class I Antibody (F21-2) [NBP1-28304] - Chicken peripheral blood mononuclear cells were double-stained with mouse anti-chicken MHC Class I-FITC and mouse anti-chicken IgM-PE. Small lymphocytes were then gated and analyzed on a FACScan™ flow cytometer (BDIS, San Jose, CA).
NBP1-28305 - MHC Class I
Flow cytometry: MHC Class I Antibody (F21-2) [NBP1-28305] - 1 ug/10^6 Chicken peripheral blood mononuclear cells were double-stained with mouse anti-chicken MHC Class I-FITC and mouse anti-chicken IgM-PE. Small lymphocytes were then gated and analyzed on a flow cytometer
NBP1-28306 - MHC Class I
Flow cytometry / FACS analysis: MHC Class I Antibody (F21-2) [Biotin] [NBP1-28306] - Chicken peripheral blood mononuclear cells were double-stained with mouse anti-chicken MHC Class I-FITC and mouse anti-chicken IgM-PE. Small lymphocytes were then gated and analyzed on a FACScan™ flow cytometer (BDIS, San Jose, CA).

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

MHC Class I antibody
MHC Class I Mouse IgG1 F21-2 Biotin Chk, Tr F
0.5 mg / €450.00
  OriGene Technologies GmbH

MHC Class I antibody
Immunofluorescent Staining: Chicken peripheral blood mononuclear cells were double-stained with Mouse anti-Chicken MHC Class I-FITC and Mouse anti-Chicken IgM-PE. Small lymphocytes were then gated and analyzed on a FACScan(TM) flow cytometer (BDIS, San Jose, CA). Amount Used: 1 µg/10e6 cells. Mouse IgG1 F21-2 FITC Chk, Tr F
0.5 mg / €500.00
  OriGene Technologies GmbH

MHC Class I antibody
MHC Class I Mouse IgG1 F21-2 Purified Chk, Tr C, F, IP, WB
0.5 mg / €370.00
  OriGene Technologies GmbH

MHC Class I antibody
MHC Class I Mouse IgG1 F21-2 PE Chk, Tr F
0.1 mg / €340.00
  OriGene Technologies GmbH

MHC Class I (monomorphic) antibody
MHC Class I Mouse IgG2b 2G5 FITC Bov, GP, Hst, Hu, Ms, Por, Rt F
0.1 mg / €400.00
  OriGene Technologies GmbH

MHC Class I (monomorphic) antibody
MHC Class I Mouse IgG2b 2G5 Purified Bov, GP, Hst, Hu, Ms, Por, Sh F, IP
0.25 mg / €460.00
  OriGene Technologies GmbH

6 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (6)
Clonality
  1. Monoclonal (6)
Target
  1. MHC Class I (6)
Property
  1. monomorphic (2)
Reactivity
  1. Chicken (Chk) (4)
  2. Turkey (4)
  3. Bovine (Bov) (2)
  4. Guinea Pig (GP) (2)
  5. Hamster (Hst) (2)
  6. Human (Hu) (2)
  7. Mouse (Ms) (2)
  8. Porcine (Por) (2)
  9. Rat (Rt) (1)
  10. Sheep (Sh) (1)
Applications
  1. Flow cytometry (F) (6)
  2. Immunoprecipitation (IP) (2)
  3. Frozen sections (C) (1)
  4. Western blot / Immunoblot (WB) (1)
Presentation
  1. FITC (2)
  2. Purified (2)
  3. Biotin (1)
  4. PE (1)
Host
  1. Mouse (6)
Images
  1. 1 image (1)
Images: Applications
  1. Flow cytometry (F) (1)
Manufacturer
  1. OriGene Technologies (6)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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