MIA antibody
Principal name
MIA antibody
Alternative names for MIA antibody
Melanoma inhibitory activity, Melanoma-derived growth regulatory protein
Ncbi ID
9606, NP_001189482.1, NP_006524.1, NP_006524, NP_062267.2, NM_019394, NM_030852, NM_006533
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of MIA antibody
Melanoma Inhibitory Activity (MIA) was originally identified as an inhibitor of the in vitro growth of malignant melanoma cells. It was the first discovered member of a family of secreted cytokines termed the MIA/OTOR family. The four known members of this family; Melanoma Inhibitory Activity, MIA2, OTOR and TANGO each contain a Src homology-3 (SH3)-like domain. Melanoma Inhibitory Activity is an autocrine growth regulatory protein secreted from chondrocytes and malignant melanoma cells that promotes melanoma metastasis by binding competitively to fibronectin and laminin in a manner that results in melanoma cell detachment from the extracellular matrix in vivo. Elevated levels of Melanoma Inhibitory Activity may represent a clinically useful marker for diagnosis of melanoma metastasis as well as a potential marker for rheumatoid arthritis.
General readings
Blesch A, Bosserhoff AK, et al. (1994) Cancer Res 54 (21): 5695–701.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP32142PU-N | MIA antibody |
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 |
Goat | Aff - Purified | Hu | WB |
0.1 mg /
€380.00
|
||
| OriGene Technologies GmbH | |||||||
OriGene recommends this product for Western blotting. |
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| TA314721 | MIA antibody |
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| Rabbit polyclonal anti-MIA antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA328382 | MIA antibody |
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| Anti-Human MIA Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu | E, P, WB |
0.1 mg /
€275.00
|
|
| OriGene Technologies, Inc. | |||||||
| AP01143BT-N | MIA antibody |
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 |
Rabbit | Biotin | Hu | E, WB |
50 µg /
€340.00
|
||
| OriGene Technologies GmbH | |||||||
| AP01143BT-S | MIA antibody |
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|
Rabbit | Biotin | Hu | E, WB |
25 µg /
€250.00
|
||
| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP303245 | MIA |
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| Recombinant protein of human melanoma inhibitory activity (MIA) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
| TP720129 | MIA |
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| Recombinant protein of human melanoma inhibitory activity (MIA) | |||||
 |
Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
10 µg /
€299.00
|
|
| OriGene Technologies, Inc. | |||||
| TP723296 | MIA (transcript variant 1) |
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| Purified recombinant protein of Human melanoma inhibitory activity (MIA), transcript variant 1. | |||||
 |
Human | > 95 % Preparation: . Purity Detail: >95% as determined by SDS-PAGE and Coomassie blue staining. |
E. coli |
20 µg /
€230.00
|
|
| OriGene Technologies, Inc. | |||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR219062L2V | Lenti ORF particles, Mia (GFP-tagged) - Mouse melanoma inhibitory activity 1 (Mia1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR219062L1V | Lenti ORF particles, Mia (Myc-DDK-tagged) - Mouse melanoma inhibitory activity 1 (Mia1), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR214909L2V | Lenti ORF particles, Mia (GFP-tagged ORF) - Rat melanoma inhibitory activity (Mia), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR214909L1V | Lenti ORF particles, Mia (Myc-DDK-tagged ORF) - Rat melanoma inhibitory activity (Mia), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||