MMP-3 antibody
Principal name
MMP-3 antibody
Alternative names for MMP-3 antibody
Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1
Ncbi ID
NP_002413.1, 9606, NP_034939.1, 10116, NP_002413, NP_034939, NM_002422, NM_010809
Available reactivities
Available hosts
Available applications
Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)
Background of MMP-3 antibody
Matrix metalloproteinase-3 (MMP-3) also called stromelysin or transin, is a proteoglycanase closely related to collagenase (MMP1) with a wide range of substrate specificities. The complete primary structure for human MMP-3, which has 477 residues including a 17-residue signal peptide. MMP-3 and collagenase are 54% identical in sequence, suggesting a common origin for the evolution of the two proteinases. MMP-3 and collagenase expression are coordinately modulated in synovial fibroblast cultures.1 MMP-3 is a secreted metalloprotease produced predominantly by connective tissue cells. Together with other metalloproteases, it can synergistically degrade the major components of the extracellular matrix. It is capable of degrading proteoglycan, fibronectin, laminin, and type IV collagen, but not interstitial type I collagen. MMP-3 genotype may be an important determinant of vascular remodeling and age-related arterial stiffening, with the heterozygote having the optimal balance between matrix accumulation and deposition.2 The standard product used in this kit is recombinant human MMP-3, consisting of 460 amino acids with the molecular mass of 52KDa. The detected MMP-3 includes zymogen and active enzyme.
General readings
Ito, A. et al. Identification of rabbit uterine cervical procollagenase activator as rabbit matrix metalloproteinase 3 (stromelysin). Comp. Biochem. Physiol., 99B. 381-385, 1991.
Morita, Y. et al. A two-step sandwich enzyme immunoassay for rabbit proMMP-3 using monoclonal antibodies. Connect. Tissue. 27. 183-190, 1995 (In Japanese).





Lane 1: Hela whole cell lysate treated with PMA.
Lane 2: Mouse heart tissue lysate.
Lane 3: PC12 whole cell lysate treated with PMA.




































































- Quick-Filters:
- Cited (1)
- Highly Validated (4)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP06233PU-N | MMP-3 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€370.00
|
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| OriGene Technologies GmbH | |||||||
+2 additional images |
Published recently! |
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| TA590687 | MMP-3 antibody |
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| Rabbit Polyclonal MMP3 Antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, P, WB |
0.1 mg /
€409.00
|
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| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| TA806871 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI1E9 (formerly 1E9) | |||||||
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Mouse | IgG2b | OTI1E9 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+6 additional images |
Highly validated antibody! |
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| TA806979 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI2D4 (formerly 2D4) | |||||||
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Mouse | IgG1 | OTI2D4 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
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| AP23149PU-N | MMP-3 (1-35) antibody |
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Rabbit | Aff - Purified | Hu | ICC/IF, P, WB |
50 µl /
€425.00
|
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| OriGene Technologies GmbH | |||||||
+4 additional images |
Highly validated antibody! |
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| TA311231 | MMP-3 (459-473) antibody |
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| Goat Anti-MMP3 (aa459-473) Antibody | |||||||
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Goat | Aff - Purified | Hu | WB |
0.1 mg /
€360.00
|
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| OriGene Technologies, Inc. | |||||||
| TA313102 | MMP-3 antibody |
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| Rabbit polyclonal anti-MMP-3 antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
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| TA313103 | MMP-3 antibody |
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| Rabbit polyclonal MMP3 (Cleaved-Phe100) antibody | |||||||
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Rabbit | IgG | Purified | Hu | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA323014 | MMP-3 antibody |
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| Anti-MMP3 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA326993 | MMP-3 antibody |
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| MMP3 Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA327947 | MMP-3 antibody |
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| Mouse Monoclonal anti-MMP3 Antibody | |||||||
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Mouse | IgG1 | F36P1B4 | Purified | Hu | E, P, WB |
0.1 mg /
€230.00
|
| OriGene Technologies, Inc. | |||||||
| TA336495 | MMP-3 antibody |
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| Rabbit Polyclonal MMP-3 Antibody | |||||||
![]() |
Rabbit | Purified | Hu, Ms, Rt | C, P, WB |
0.1 ml /
€450.00
|
||
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA347436 | MMP-3 antibody |
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| Rabbit Polyclonal Anti-MMP3 Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA806869 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI2H6 (formerly 2H6) | |||||||
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Mouse | IgG1 | OTI2H6 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA806870 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI4B5 (formerly 4B5) | |||||||
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Mouse | IgG1 | OTI4B5 | Purified | Hu | WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
| TA806872 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI2D6 (formerly 2D6) | |||||||
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Mouse | IgG1 | OTI2D6 | Purified | Hu | WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
| TA806873 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI2D9 (formerly 2D9) | |||||||
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Mouse | IgG1 | OTI2D9 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| TA806915 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI3C6 (formerly 3C6) | |||||||
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Mouse | IgG1 | OTI3C6 | Purified | Hu | WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
| TA806916 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI2E7 (formerly 2E7) | |||||||
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Mouse | IgG2b | OTI2E7 | Purified | Hu | WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
| TA806933 | MMP-3 antibody |
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| MMP3 mouse monoclonal antibody, clone OTI2D7 (formerly 2D7) | |||||||
![]() |
Mouse | IgG2b | OTI2D7 | Purified | Hu | WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
































+2 additional images










![Western Blot: MMP3 Antibody [TA336495] - Analysis of MMP-3 (S453) antibody in extracts from 293 cells.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB100-91878-1-W.jpg)







