MRG15 antibody
Principal name
MRG15 antibody
Alternative names for MRG15 antibody
MORF4L1, MRG15, FWP006, HSPC008, HSPC061, PP368, Mortality factor 4-like protein 1, MSL3-1 protein, MORF-related gene 15 protein, Transcription factor-like protein MRG15
Ncbi ID
NP_006782, NP_006782.1, 9606, NM_001039147, NP_001252532.1, NM_006791, NM_206839, NP_001034236.1, BC017619, NM_024431, BC103783
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of MRG15 antibody
Component of the NuA4 histone acetyltransferase complex which is involved in transcriptiol activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - D interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptiol programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and D repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in D repair when directly recruited to sites of D damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombition repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to D-damage foci.
General readings
Pardo PS, Leung JK, Lucchesi JC, Pereira-Smith OM. MRG15, a Novel Chromodomain Protein, Is Present in Two Distinct Multiprotein Complexes Involved in Transcriptional Activation. J Biol Chem. 2002 Dec 27;277(52):50860-6.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA311371 | MRG15 (N-term) antibody |
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| Goat Anti-MRG15 / MORF4L1 Antibody | |||||||
 |
Goat | Aff - Purified | Bov, Can, Hu, Ms, Rt | E, P, WB |
0.1 mg /
€360.00
|
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| OriGene Technologies, Inc. | |||||||
| TA347664 | MRG15 antibody |
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| Rabbit Polyclonal Anti-MORF4L1 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA808423 | MRG15 antibody |
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| MORF4L1 mouse monoclonal antibody, clone OTI5D2 (formerly 5D2) | |||||||
 |
Mouse | IgG1 | OTI5D2 | Purified | Hu | P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
|
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| TA808426 | MRG15 antibody |
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| MORF4L1 mouse monoclonal antibody, clone OTI7B5 (formerly 7B5) | |||||||
 |
Mouse | IgG2b | OTI7B5 | Purified | Hu | WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
|
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| AP01243PU-N | MRG15 antibody |
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 |
Rabbit | Aff - Purified | Hu, Ms | ICC/IF, P, WB |
0.1 mg /
€370.00
|
||
| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP300251 | MRG15 (transcript variant 1) |
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| Recombinant protein of human mortality factor 4 like 1 (MORF4L1), transcript variant 1 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY402027 | MORF4L1 overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. | ||
| LY404237 | MORF4L1 overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. | ||
| LY430951 | MORF4L1 overexpression lysate |
|
|
0.1 mg /
€315.00
|
|
| OriGene Technologies, Inc. |