MTUS1 antibody
Principal name
MTUS1 antibody
Alternative names for MTUS1 antibody
ATIP, GK1, KIAA1288, MTSG1, AT2 receptor-binding protein, Mitochondrial tumor suppressor 1, Angiotensin-II type 2 receptor-interacting protein
Ncbi ID
9606, NP_001001924, NP_065800, NM_001001931, NP_001001924.1, NP_001005863.1, BC041777, NM_001005863, NM_001005865, NM_020749, NM_001001925, NM_001166393
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of MTUS1 antibody
MTUS1 contains a C-terminal domain and is able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. One of the isoforms has been shown to be a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other isoforms may be nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.This gene encodes a protein which contains a C-terminal domain able to interact with the angiotension II (AT2) receptor and a large coiled-coil region allowing dimerization. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and partcipates in AT2 signaling pathways. Other variants may encode nuclear or transmembrane proteins but it has not been determined whether they also participate in AT2 signaling pathways.
General readings
Nouet,S., (2004) J. Biol. Chem. 279 (28), 28989-28997
MTUS1 monoclonal antibody (M01), clone 1C7. Western Blot analysis of MTUS1 expression in human colon.
Detection limit for recombinant GST tagged MTUS1 is approximately 0.3ng/ml as a capture antibody.
Total; WB Suggested Anti-MTUS1 Antibody Titration: Positive Control: Total Cell Lysates; MTUS1 antibody - N-terminal region (ARP44418_T100) in Total cells using Western Blot
Human Pineal Tissue; Rabbit Anti-MTUS1 Antibody . Catalog Number: ARP44419_P050 . Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue . Observed Staining: Cytoplasmic and membrane in cell bodies of pinealocytes and their processes . Primary Antibody Concentration: 1:100 . Other Working Concentrations: 1/600 . Secondary Antibody: Donkey anti-Rabbit-Cy3 . Secondary Antibody Concentration: 1:200 . Magnification: 20X . Exposure Time: 0.5 - 2.0 sec .; Rabbit Anti-MTUS1 Antibody (ARP44419_P050) ) in Human Pineal Tissue using Immunohistochemistry
Human HepG2; Host: Rabbit. Target Name: EGFL8 . Sample Tissue: HepG2 . Antibody Dilution: 1.0ug/ml.. MTUS1 is strongly supported by BioGPS gene expression data to be expressed in HepG2.; MTUS1 antibody - middle region (ARP44419_P050) in Human HepG2 cells using Western Blot
Hum. Fetal Heart; Host: Rabbit. Target Name: GNAS . Sample Tissue: Human Fetal Heart . Antibody Dilution: 1.0ug/ml.; MTUS1 antibody - middle region (ARP44419_P050) in Hum. Fetal Heart cells using Western Blot
Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; MTUS1 antibody - middle region (ARP44419_P050) in Hum. Adult Placenta cells using Western Blot
Hum. Adult Placenta; Host: Rabbit. Target Name: CHAD . Sample Tissue: Human Adult Placenta . Antibody Dilution: 1.0ug/ml.; MTUS1 antibody - middle region (ARP44419_P050) in Hum. Adult Placenta cells using Western Blot
Hum. Fetal Lung; Host: Rabbit. Target Name: NSUN6 . Sample Tissue: Human Fetal Lung . Antibody Dilution: 1.0ug/ml.; MTUS1 antibody - middle region (ARP44419_P050) in Hum. Fetal Lung cells using Western Blot
Human MCF-7, HeLa, and human cancer; MTUS1 antibody - middle region (ARP44419_P050) validated by WB using MCF-7, HeLa, and human cancer cell lines at 1:2000.; MTUS1 antibody - middle region (ARP44419_P050) in Human MCF-7, HeLa, and human cancer cells using Western Blot
Human HeLa; WB Suggested Anti-MTUS1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Hela cell lysate. MTUS1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells.; MTUS1 antibody - middle region (ARP44419_P050) in Human HeLa cells using Western Blot
Human MCF-7, HeLa, and human cancer; MTUS1 antibody - middle region (ARP44419_P050) validated by WB using MCF-7, HeLa, and human cancer cell lines at 1:2000.; MTUS1 antibody - middle region (ARP44419_P050) in Human MCF-7, HeLa, and human cancer cells using Western Blot
WB Suggested Anti-MTUS1 Antibody Titration: Positive Control: Total Cell Lysates
MTUS1 antibody - middle region validated by WB using MCF-7, HeLa, and human cancer cell lines at 1: 2000.
MTUS1 antibody - middle region validated by WB using MCF-7, HeLa, and human cancer cell lines at 1: 2000.
3Hum. Adult Placenta; Host: Rabbit; Target Name: CHAD; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0 ug/ml
4Hum. Fetal Lung; Host: Rabbit; Target Name: NSUN6; Sample Tissue: Human Fetal Lung; Antibody Dilution: 1.0 ug/ml
5Hum. Fetal Heart; Host: Rabbit; Target Name: GNAS; Sample Tissue: Human Fetal Heart; Antibody Dilution: 1.0 ug/ml
6Human HepG2; Host: Rabbit; Target Name: EGFL8; Sample Tissue: HepG2; Antibody Dilution: 1.0 ug/ml.MTUS1 is strongly supported by BioGPS gene expression data to be expressed in HepG2
7Hum. Adult Placenta; Host: Rabbit; Target Name: CHAD; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0 ug/ml
WB Suggested Anti-MTUS1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: Hela cell lysate.MTUS1 is strongly supported by BioGPS gene expression data to be expressed in Human HeLa cells
Rabbit Anti-MTUS1 Antibody; Formalin Fixed Paraffin Embedded Tissue: Human Pineal Tissue; Observed Staining: Cytoplasmic and membrane in cell bodies of pinealocytes and their processes; Primary Antibody Concentration: 1: 100; Other Working Concentrations:
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (MTUS1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using (MTUS1 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA350192 | MTUS1 antibody |
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| Rabbit Polyclonal Anti-MTUS1 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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Lysates
| Catalog No. | ||
|---|---|---|
| LY424280 | MTUS1 overexpression lysate |
|
 |
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC222093L2V | Lenti ORF particles, MTUS1 (mGFP-tagged)-Human microtubule associated tumor suppressor 1 (MTUS1), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,530.00
|
|
| OriGene Technologies, Inc. | ||
| RC230037L2V | Lenti ORF particles, MTUS1 (mGFP-tagged) - Human microtubule associated tumor suppressor 1 (MTUS1), transcript variant 6, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,110.00
|
|
| OriGene Technologies, Inc. | ||
| RC222093L1V | Lenti ORF particles, MTUS1 (Myc-DDK-tagged)-Human microtubule associated tumor suppressor 1 (MTUS1), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,280.00
|
|
| OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR211056L2V | Lenti ORF particles, Mtus1 (GFP-tagged) - Mouse mitochondrial tumor suppressor 1 (cDNA clone MGC:31380 IMAGE:4240274), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,470.00
|
|
| OriGene Technologies, Inc. | ||
| MR211806L2V | Lenti ORF particles, Mtus1 (GFP-tagged) - Mouse mitochondrial tumor suppressor 1 (Mtus1), nuclear gene encoding mitochondrial protein, transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,180.00
|
|
| OriGene Technologies, Inc. | ||
| MR211056L1V | Lenti ORF particles, Mtus1 (Myc-DDK-tagged) - Mouse mitochondrial tumor suppressor 1 (cDNA clone MGC:31380 IMAGE:4240274), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,330.00
|
|
| OriGene Technologies, Inc. | ||
| MR211806L1V | Lenti ORF particles, Mtus1 (Myc-DDK-tagged) - Mouse mitochondrial tumor suppressor 1 (Mtus1), nuclear gene encoding mitochondrial protein, transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,960.00
|
|
| OriGene Technologies, Inc. | ||