MYBPC3 antibody
Principal name
MYBPC3 antibody
Alternative names for MYBPC3 antibody
cardiac-type Myosin-binding protein C, C-protein cardiac muscle isoform
Gene ID
4607 (MYBPC3)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of MYBPC3 antibody
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Immunohistochemistry analysis in human heart tissue (Formalin-fixed, Paraffin-embedded) using MYBPC3 antibody Cat.-No. AP52783PU-N (N-term), followed by peroxidase conjugated secondary antibody and DAB staining. This data demonstrates the use of this antibody for IHC. Clinical relevance has not been evaluated.
Western blot analysis in mouse heart tissue lysates (35ug/lane) using MYBPC3 antibody Cat.-No. AP52783PU-N (N-term). This demonstrates this antibody detected the MYBPC3 protein (arrow).
Immunohistochemistry analysis of paraffin-embedded human heart tissue using MYBPC3 antibody.The picture on the right is treated with the synthesized peptide.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA314224 | MYBPC3 antibody |
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| Rabbit polyclonal anti-MYBPC3 antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| AP52783PU-N | MYBPC3 (N-term) antibody |
||||||
 |
Rabbit | Ig | Aff - Purified | Hu, Ms | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP317720 | MYBPC3 |
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| Purified recombinant protein of Homo sapiens myosin binding protein C, cardiac (MYBPC3) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€788.00
|
|
| OriGene Technologies, Inc. | |||||