MYL3 antibody
Principal name
MYL3 antibody
Alternative names for MYL3 antibody
Myosin light chain 3, Myosin light chain 1, slow-twitch muscle B/ventricular isoform, MLC1SB, Cardiac myosin light chain 1, CMLC1, Ventricular/slow twitch myosin alkali light chain
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)
Background of MYL3 antibody
Myosins are a large superfamily of motor proteins that move along actin filaments, while hydrolyzing ATP. Myosin is the major component of thick muscle filaments, and is a long asymmetric molecule containing a globular head and a long tail. The molecule consists of two heavy chains and four light chains. Activation of smooth and cardiac muscle primarily involves pathways which increase calcium and myosin phosphorylation resulting in contraction. Myosin light chain phosphatase acts to regulate muscle contraction by dephosphorylating activated myosin light chain. MYL3 encodes myosin light chain 3, an alkali light chain also referred to in the literature as both the ventricular isoform and the slow skeletal muscle isoform. Human myosin light chain has clinical application as a cardiac marker. Mutations in MYL3 have been identified as a cause of mid-left ventricular chamber type hypertrophic cardiomyopathy.














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- Highly Validated (1)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AM06334SU-N | MYL3 antibody |
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Mouse | IgG1 | 7C1 | Ascites | Hu | E, P, WB |
0.1 ml /
€420.00
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| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
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| TA311754 | MYL3 antibody |
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| Rabbit polyclonal anti-MYL3 antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, WB |
0.1 ml /
€335.00
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|
| OriGene Technologies, Inc. | |||||||
| TA350194 | MYL3 antibody |
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| Rabbit Polyclonal Anti-MYL3 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
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| AM06333SU-N | MYL3 antibody |
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Mouse | IgG1 | 3F8 | Ascites | Hu | E, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies GmbH | |||||||
+2 additional images |
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| DP2015 | MYL3 antibody |
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Rabbit | Aff - Purified | Hu | E, WB |
50 µg /
€390.00
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| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP303122 | MYL3 |
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| Recombinant protein of human myosin, light chain 3, alkali; ventricular, skeletal, slow (MYL3) | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||





+3 additional images



