NCAPH2 antibody

Principal name

NCAPH2 antibody

Alternative names for NCAPH2 antibody

CAPH2, Chromosome-associated protein H2

SwissProt ID

Q4V8I2 (Rat), Q6IBW4 (Human), Q8BSP2 (Mouse)

Gene ID

29781 (NCAPH2), 52683 (Ncaph2), 300149

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of NCAPH2 antibody

Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.

General readings

Ono,T., (2003) Cell 115 (1), 109-121

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NCAPH2 (N-term) antibody

Western blot analysis of anti-NCAPH2 (AP11816PU-N) in HepG2 cell line lysate (35 µg/lane). NCAPH2 (arrow) was detected using the purified Pab (1:60 dilution). Rabbit Ig Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NCAPH2 (transcript variant 1)

  Purified recombinant protein of Homo sapiens non-SMC condensin II complex, subunit H2 (NCAPH2), transcript variant 1  
NCAPH2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

NCAPH2 overexpression lysate

NCAPH2 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

NCAPH2 overexpression lysate

NCAPH2 overexpression lysate  
0.1 mg / €315.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ncaph2 (GFP-tagged) - Mouse non-SMC condensin II complex, subunit H2 (Ncaph2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Ncaph2 (GFP-tagged) - Mouse non-SMC condensin II complex, subunit H2 (Ncaph2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,340.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ncaph2 (Myc-DDK-tagged) - Mouse non-SMC condensin II complex, subunit H2 (Ncaph2), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Ncaph2 (Myc-DDK-tagged) - Mouse non-SMC condensin II complex, subunit H2 (Ncaph2), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,200.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Ncaph2 (GFP-tagged ORF) - Rat non-SMC condensin II complex, subunit H2 (Ncaph2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ncaph2 (GFP-tagged ORF) - Rat non-SMC condensin II complex, subunit H2 (Ncaph2), 200 uL, >10^7 TU/mL  
200 µl / €1,260.00
  OriGene Technologies, Inc.

Lenti ORF particles, Ncaph2 (Myc-DDK-tagged ORF) - Rat non-SMC condensin II complex, subunit H2 (Ncaph2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Ncaph2 (Myc-DDK-tagged ORF) - Rat non-SMC condensin II complex, subunit H2 (Ncaph2), 200 uL, >10^7 TU/mL  
200 µl / €1,130.00
  OriGene Technologies, Inc.

8 Item(s)

per page
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