NDUFA1 antibody
Principal name
NDUFA1 antibody
Alternative names for NDUFA1 antibody
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
SwissProt ID
O15239 (Human)
Gene ID
4694 (NDUFA1)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)
Background of NDUFA1 antibody
NDUFA1（NADH-UBIQUINONE OXIDOREDUCTASE 1 ALPHA SUBCOMPLEX, 1）,also called MWFE, B. TAURUS, HOMOLOG OF, encodes a subunit of mitochondrial NADH:ubiquinone oxidoreductase, also known as mitochondrial complex I. The NDUFA1 gene is mapped to chromosome Xq24. The deduced polypeptide sequence of NDUFA1 was found to have an N-terminal hydrophobic domain, likely to be a transmembrane domain, and a C-terminal hydrophilic domain. And the NDUFA1 gene contains 3 exons and spans about 5.0 kb of genomic DNA. Complementation with hamster Ndufa1 cDNA restored the rotenone-sensitive complex I activity of these mutant cells to approximately 100% of the parent cell activity. The findings established that the MWFE polypeptide is absolutely essential for an active complex I in mammals. The NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA350206 | NDUFA1 antibody |
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| Rabbit Polyclonal Anti-NDUFA1 Antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, P, WB |
0.1 ml /
€335.00
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| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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