NOS1AP antibody

Principal name

NOS1AP antibody

Alternative names for NOS1AP antibody

CAPON, KIAA0464, Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

SwissProt ID

O54960 (Rat), O75052 (Human), Q9D3A8 (Mouse)

Gene ID

9722 (NOS1AP)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Goat, Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Flow Cytometry (F), Frozen Sections (C)

Background of NOS1AP antibody

The NOS1AP gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms.

General readings

Bailey, S.D. et al., Diabetes Care 33(10): 2250-2253 (2010)
Lu, J. et al., Diabet. Med. 27(9): 1074-1079 (2010)
Husted, J.A. et al., Schizophr. Res. 121 (1-3): 187-192 (2010)
Tomas, M. et al., J. Am. Coll. Cardiol. 55(24): 2745-2752(2010)
Delorme, R. et al., BMC Med. Genet. 11: 108 (2010)

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Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

NOS1AP (full length, N-term HIS tag, transcript variant 1)

  Purified recombinant protein of Human nitric oxide synthase 1 (neuronal) adaptor protein (NOS1AP), transcript variant 1, full length, with N-terminal HIS tag, expressed in E. coli, 50ug  
NOS1AP Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €205.00
  OriGene Technologies, Inc.

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