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NUP107 antibody

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Principal name

NUP107 antibody

Alternative names for NUP107 antibody

Nucleoporin Nup107, NUP84, Nuclear pore complex protein Nup107

SwissProt ID

P52590 (Rat), P57740 (Human), Q8BH74 (Mouse)

Gene ID

57122 (NUP107), 103468 (Nup107)

Ncbi ID

9606, NP_065134.1, NP_065134, P57740, NP_598771.1

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of NUP107 antibody

The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-107 is part of the hetero-oligomeric complex that also contains NUP160, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP107 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP107 may be an important drug target in HIV treatment. Multiple isoforms of NUP107 are known to exist.

General readings

Kim, S.Y., et al. Biochem. Biophys. Res. Commun. 401(1):131-136(2010)
Kamatani, Y., et al. Nat. Genet. 42(3):210-215(2010)
Mishra, R.K., et al. Nat. Cell Biol. 12(2):164-169(2010)
Platani, M., et al. Mol. Biol. Cell 20(24):5260-5275(2009)
Whittle, J.R., et al. J. Biol. Chem. 284(41):28442-28452(2009)

PAB13392 - NUP107
Western blot analysis of NUP107 in A-549 cell lysate with NUP107 polyclonal antibody ( Cat # PAB13392 ) at ( A ) 1 and ( B ) 2 µg/ml.
PAB13393 - NUP107
Western blot analysis of NUP107 in A-549 cell lysate with NUP107 polyclonal antibody ( Cat # PAB13393 ) at ( A ) 1 and ( B ) 2 µg/ml.
AP23855PU-N - NUP107
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
AP23855PU-N - NUP107
Western blot analysis of NUP107 in A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 µg/ml.
AP52969PU-N - NUP107
Immunohistochemistry analysis in formalin fixed and paraffin embedded human cervical tissue reacted with NUP107 Antibody (Center) Cat.-No AP52969PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.
AP52969PU-N - NUP107
Western blot analysis of NUP107 Antibody (Center) Cat.-No AP52969PU-N in mouse NIH-3T3 cell line lysates (35ug/lane). This demonstrates the NUP107 antibody detected the NUP107 protein (arrow).
TA306611 - NUP107
Western blot analysis of NUP107 in A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL.
TA306611 - NUP107
Immunocytochemistry of NUP107 in A549 cells with NUP107 antibody at 10 ug/mL.
TA306611 - NUP107
Immunofluorescence of NUP107 in A549 cells with NUP107 antibody at 10 ug/mL.
TA306612 - NUP107
Western blot analysis of NUP107 in A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL.
TA306612 - NUP107
Immunocytochemistry of NUP107 in A549 cells with NUP107 antibody at 2.5 ug/mL.
TA306612 - NUP107
Immunofluorescence of NUP107 in A549 cells with NUP107 antibody at 10 ug/mL.
TA311490 - NUP107
(1ug/ml) staining of Peripheral Blood Lymphocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

5 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

NUP107 antibody
  Rabbit Polyclonal NUP107 Antibody  
Western blot analysis of NUP107 in A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

NUP107 (C-term) antibody
  Rabbit Polyclonal NUP107 Antibody  
Western blot analysis of NUP107 in A549 cell lysate with NUP107 antibody at (A) 1 and (B) 2 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

NUP107 antibody
  Goat Anti-NUP107 Antibody  
(1ug/ml) staining of Peripheral Blood Lymphocytes lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

NUP107 antibody
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €425.00
  OriGene Technologies GmbH
+1 additional image

NUP107 (Center) antibody
Immunohistochemistry analysis in formalin fixed and paraffin embedded human cervical tissue reacted with NUP107 Antibody (Center) Cat.-No AP52969PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu, Ms P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

5 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (5)
Clonality
  1. Polyclonal (5)
Target
  1. NUP107 (5)
Property
  1. C-term (1)
  2. Center (1)
Reactivity
  1. Human (Hu) (5)
  2. Mouse (Ms) (5)
  3. Rat (Rt) (4)
  4. Bovine (Bov) (1)
  5. Canine (Can) (1)
Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Enzyme Immunoassay (E) (3)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  4. Paraffin Sections (P) (2)
Presentation
  1. Aff - Purified (4)
  2. Purified (1)
Host
  1. Rabbit (4)
  2. Goat (1)
Images
  1. 1 image (5)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Immunofluorescence (IF) (2)
  3. Paraffin Sections (P) (2)
Manufacturer
  1. OriGene Technologies (5)
Service
  • OriGene Technologies GmbH
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