Nurim antibody
Principal name
Nurim antibody
Alternative names for Nurim antibody
NRM, Nuclear rim protein, Nuclear envelope membrane protein
Ncbi ID
9606, NP_009174.1, NP_009174, NM_212508, NM_007243, NP_598883.1
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of Nurim antibody
Nurim is an inner nuclear membrane (INM) protein that was first isolated in a visual screen for nuclear envelope-localizing proteins. Nurim lacks an N-terminal domain characteristic of other INM proteins examined to date and may represent a class of proteins that localize to the INM by a distinct mechanism. It is indicated that Nurim is a six transmembrane-spanning protein and contains a hairpin turn in its C-terminal transmembrane domain, resulting in the N and C termini residing on the same side of the membrane. A loop region between the fourth and fifth transmembrane domains is exposed toward the nucleoplasm and contains a region accessible for site-specific endoproteinase cleavage. In biochemical fractionation, Nurim remained extremely tightly bound to nuclear fractions. Under conditions in which nuclear lamins were completely extracted, a significant population of nurim remained resistant to solubilization. This tight binding requires the C-terminal region of the protein. Consideration of sequence alignments and identification of specific topological features of Nurim indicate that it may possess enzymatic function.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP08398PU-N | Nurim (200-250) antibody |
||||||
 |
Rabbit | IgG | Aff - Purified | Hu, Ms | P, WB |
50 µg /
€425.00
|
|
| OriGene Technologies GmbH | |||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP308090 | Nurim |
||||
| Recombinant protein of human nurim (nuclear envelope membrane protein) (NRM) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR214970L2V | Lenti ORF particles, Nrm (GFP-tagged ORF) - Rat nurim (nuclear envelope membrane protein) (Nrm), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR214970L1V | Lenti ORF particles, Nrm (Myc-DDK-tagged ORF) - Rat nurim (nuclear envelope membrane protein) (Nrm), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||