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ORAI2 antibody

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Principal name

ORAI2 antibody

Alternative names for ORAI2 antibody

Protein orai-2, C7orf19, CBCIP2, TMEM142B, Transmembrane protein 142B, CAP-binding protein complex-interacting protein 2

SwissProt ID

Q5ZLW2 (Chick), Q8BH10 (Mouse), Q96SN7 (Human)

Gene ID

80228 (ORAI2), 269717 (Orai2)

Ncbi ID

NP_001119812.1, 9606, NP_116220, NM_032831, NM_001126340, Q96SN7, NP_848866.2

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of ORAI2 antibody

Cytosolic Ca2+ has long been known to act as a key second messenger in many intracellular pathways including syptic transmission, muscle contraction, hormol secretion, and cell growth and proliferation. The mechanism controlling intracellular Ca2+ level influx, either by the calcium-release-activated Ca2+ channels (CRAC) or from intracellular stores, has become of great interest. Recently, several key players of the store-operated complex have been identified: the Orai family consisting of three members, Orai1-3, and the STIM family, which consists of two members, STIM1 and STIM2. Orai1 (also known as CRACM1) acts as the store-operated calcium channel (SOC) and STIM1 as the endoplasmic reticulum Ca2+ sensor. Orai1, Orai2, and Orai3 are all capable of forming store-operated channels. Co-expresssion of Orai2 and STIM1 was shown to produce currents that appear similar but smaller than those produced by co-expression of Orai1 and STIM1. Orai2 transcripts are predomintly expressed in kidney, lung, and spleen, and it appears that Orai2 is the only Orai isoform with multiple transcripts.

General readings

DeHaven,W.I., (2007) J. Biol. Chem. 282 (24), 17548-17556

AP07374PU-N - ORAI2
Placenta: Formalin-Fixed Paraffin-Embedded (FFPE)
AP07374PU-N - ORAI2
Skeletal muscle: Formalin-Fixed Paraffin-Embedded (FFPE)
ARP50131_P050 - ORAI2
Human MCF-7; WB Suggested Anti-ORAI2 Antibody Titration: 0.2-1 ug/ml. Positive Control: MCF7 cell lysate; ORAI2 antibody - middle region (ARP50131_P050) in Human MCF-7 cells using Western Blot
PAB12991 - ORAI2
Immunocytochemistry of ORAI2 in Jurkat cells with ORAI2 polyclonal antibody ( Cat # PAB12991 ) at 5 µg/ml.
PAB12991 - ORAI2
Western blot analysis of ORAI2 in Jurkat cell lysate with ORAI2 polyclonal antibody ( Cat # PAB12991 ) at ( A ) 1, ( B ) 2 and ( C ) 4 µg/ml.
TA807500 - ORAI2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ORAI2 (RC221137, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ORAI2.(1:500)
TA306419 - ORAI2
Western blot analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL.
TA306419 - ORAI2
Immunocytochemistry of ORAI2 in Jurkat cells with ORAI2 antibody at 5 ug/mL.
TA306419 - ORAI2
Immunofluorescence of ORAI2 in Jurkat cells with ORAI2 antibody at 20 ug/mL.
TA328751 - ORAI2
Western blot analysis of HL-60 (lanes 1 and 3) and Jurkat (lanes 2 and 4) cell lysates: 1, 2. Anti-Orai2 antibody, (1:200). 3, 4. Anti-Orai2 antibody, preincubated with the control peptide antigen.
TA328751 - ORAI2
Expression of Orai2 in rat lung. Immunohistochemical staining of paraffin-embedded rat lung sections using Anti-Orai2 antibody, (1:100). Strong and specific staining is evident in bronchiolar epithelium (blue) and alveoli walls (red). Hematoxilin is used as the counterstain.
TA339631 - ORAI2
WB Suggested Anti-ORAI2 Antibody Titration: 0.2-1 ug/ml; Positive Control: MCF7 cell lysate

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ORAI2 (C-term) antibody
  Rabbit Polyclonal ORAI2 Antibody  
Western blot analysis of ORAI2 in Jurkat cell lysate with ORAI2 antibody at (A) 1, (B) 2 and (C) 4 ug/mL. Rabbit IgG Aff - Purified Hu, Ms E, ICC/IF, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

ORAI2 antibody
  Rabbit Polyclonal Anti-Orai2  
Western blot analysis of HL-60 (lanes 1 and 3) and Jurkat (lanes 2 and 4) cell lysates: 1, 2. Anti-Orai2 antibody, (1:200). 3, 4. Anti-Orai2 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Rt WB
0.2 ml / €585.00
  OriGene Technologies, Inc.
+1 additional image

ORAI2 antibody
  ORAI2 mouse monoclonal antibody, clone OTI8D11 (formerly 8D11)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ORAI2 (RC221137, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ORAI2.(1:500) Mouse IgG2b OTI8D11 Purified Hu WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
 

TrueMAB

ORAI2 antibody
Placenta: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms P, WB
50 µg / €425.00
  OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.    

ORAI2 overexpression lysate
ORAI2 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

ORAI2 overexpression lysate
ORAI2 overexpression lysate  
0.1 mg / €315.00
  OriGene Technologies, Inc.

6 Item(s)

per page

Available Filters

Product Type
  1. Lysate (2)
  2. Primary Antibody (4)
Clonality
  1. Polyclonal (3)
  2. Monoclonal (1)
Target
  1. ORAI2 (4)
Property
  1. C-term (1)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (2)
  3. Rat (Rt) (1)
Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Enzyme Immunoassay (E) (1)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  4. Paraffin Sections (P) (1)
Presentation
  1. Aff - Purified (2)
  2. Purified (2)
Host
  1. Rabbit (3)
  2. Mouse (1)
Images
  1. 1 image (4)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Immunofluorescence (IF) (1)
  3. IHC (1)
  4. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (6)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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  • orders: ordering-de@origene.com
 
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