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PAK6 antibody

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Principal name

PAK6 antibody

Alternative names for PAK6 antibody

p21-activated kinase 6, PAK-6, Serine/threonine-protein kinase PAK 6, PAK5, PAK-5

SwissProt ID

Q3ULB5 (Mouse), Q5R8Z4 (Ponab), Q9NQU5 (Human)

Gene ID

106821730 (BUB1B-PAK6), 56924 (PAK6), 214230 (Pak6)

Ncbi ID

NP_001122100.1, 9606, NM_020168, NP_064553.1, NP_065074.1, NP_064553, NP_001122100, NP_001028426.2, NM_001145854, NM_001033254, NM_001128629, NM_001128628

Available reactivities

Av (Birds), Bt (Bat), Bov (Bovine), Can (Canine), Eq (Equine), Gt (Goat), Hu (Human), Mky (Monkey), Ms (Mouse), Prim (Primate), Rb (Rabbit), Rt (Rat), Xen (Xenopus), Bear

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PAK6 antibody

Serine/threonine-protein kinase PAK 6(p21 Protein-activated Kinase 6) is an enzyme that in humans is encoded by the PAK6 gene. The PAK6 gene is mapped to chromosome 15q15.1 based on an alignment of the PAK6 sequence with the genomic sequence. This gene encodes a protein that shares a high degree of sequence similarity with p21-activated kinase (PAK) family members. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. The p21-activated protein kinase 6 gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen.

General readings

Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)
Guey, L.T., et al. Eur. Urol. 57(2):283-292(2010)
Lee, E.J., et al. Oncol. Res. 18(9):401-408(2010)
Hosgood, H.D. III, et al. Respir Med 103(12):1866-1870(2009)
Shen, M., et al. Environ. Mol. Mutagen. 50(4):285-290(2009)

AP07004PU-N - PAK6
Testis: Formalin-Fixed Paraffin-Embedded (FFPE)
PAB2303 - PAK6
Western blot analysis of PAK6 polyclonal antibody ( Cat # PAB2303 ) in lysates from transiently transfected COS-7 cells.Lane 1 : negative control.Lane 2 : PAK1-expressing cells.Lane 3 : PAK2-expressing cellsLane 4 : PAK4-expressing cells.Lane 5 : PAK5-expressing cells.Lane 6 : PAK6-expressing cells.PAK6 ( arrow ) was detected using purified polyclonal antibody. Data is kindly provided by Drs. Z.M. Jaffer and J. Chernoff from the Fox Chase Cancer Center ( Philadelphia, PA ) .
AP14810PU-N - PAK6
Western blot analysis of anti-PAK6 Pab in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK6 (arrow) was detected using purified Pab.
H00056924-B01 - PAK6
Western Blot analysis of PAK6 expression in transfected 293T cell line (H00056924-T02) by PAK6 MaxPab polyclonal antibody.Lane 1: PAK6 transfected lysate(74.90 KDa).Lane 2: Non-transfected lysate.
H00056924-D01P - PAK6
Western Blot analysis of PAK6 expression in transfected 293T cell line (H00056924-T02) by PAK6 MaxPab polyclonal antibody.Lane 1: PAK6 transfected lysate(74.90 KDa).Lane 2: Non-transfected lysate.
H00056924-D01P - PAK6
PAK6 MaxPab rabbit polyclonal antibody. Western Blot analysis of PAK6 expression in HeLa.
PAB12890 - PAK6
Immunocytochemistry of PAK6 in Raji cells with PAK6 polyclonal antibody ( Cat # PAB12890 ) at 10 µg/ml.
PAB12890 - PAK6
Western blot analysis of PAK6 in Raji lysate with PAK6 polyclonal antibody ( Cat # PAB12890 ) at 1, 2, and 4 µg/ml.
PAB7884 - PAK6
Western blots of human PAK6 recombinant protein phosphorylated by ERK2. The blot was exposed to lambda phosphatase (lane 2) then probed with PAK6 polyclonal antibody ( Cat # PAB7884 ). The PAK6 antibody was used in the presence of a non-specific peptide (lane 3) or PAK6 (N-terminal) peptide (lane 4).
PAB7902 - PAK6
Western blots of human PAK6 recombinant protein phosphorylated by ERK2. The blot was exposed to lambda phosphatase (lane 2) then probed with PAK6 (phospho S165) polyclonal antibody ( Cat # PAB7902 ) (lanes 1-4). The PAK6 antibody was used in the presence of PAK6 (Ser-165) antibody was used in the presence of phospho-PAK6 (Ser-165) peptide (lane 3) or a non-specific phospho-serine peptide (lane 4).
AP55829PU-S - PAK6
Western blot analysis of extracts from HeLa cells (Lane 2), using PAK5/6 (Phospho-Ser602/Ser560) Antibody AP55829PU-N. The lane on the left is treated with antigen-specific peptide.
CPA2725-100ul - PAK6
Western blot analysis of PAK6 expression in HeLa (A); LOVO (B); mouse brain (C); rat brain (D) whole cell lysates.
TP723907 - PAK6
TP723908 - PAK6
TA306114 - PAK6
Western blot analysis of PAK6 in Raji lysate with PAK6 antibody at (A) 1, (B) 2, and (C) 4 ug/mL.
TA306114 - PAK6
Immunocytochemistry of PAK6 in Raji cells with PAK6 antibody at 10 ug/mL.
TA306114 - PAK6
Immunofluorescence of PAK6 in Raji cells with PAK6 antibody at 10 ug/mL.
TA324474 - PAK6
PAK6 Antibody (Center) (Cat. #TA324474) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAK6 antibody detected the PAK6 protein (arrow).
TA324474 - PAK6
PAK6 Antibody (Center) (Cat. #TA324474)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of PAK6 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
TA324474 - PAK6
Confocal immunofluorescent analysis of PAK6 Antibody (Center)(Cat#TA324474) with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
TA340992 - PAK6
Anti-PAK6 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA340992 - PAK6
Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA341010 - PAK6
Anti-PAK6 antibody IHC of human brain, neurons and glia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA349427 - PAK6
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using (PAK6 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)
TA349427 - PAK6
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (PAK6 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200)

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PAK6 antibody
  Rabbit Polyclonal PAK6 Antibody  
Western blot analysis of PAK6 in Raji lysate with PAK6 antibody at (A) 1, (B) 2, and (C) 4 ug/mL. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

PAK6 (Center) antibody
  Rabbit polyclonal PAK6 Antibody (Center)  
PAK6 Antibody (Center) (Cat. #TA324474) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the PAK6 antibody detected the PAK6 protein (arrow). Rabbit Ig Aff - Purified Hu ICC/IF, P, WB
0.4 ml / €415.00
  OriGene Technologies, Inc.
+2 additional images

PAK6 antibody
  Rabbit Polyclonal Anti-PAK6 Antibody (Linker Domain)  
PAK6 Rabbit Aff - Purified Hu P
50 µg / €425.00
  OriGene Technologies, Inc.

PAK6 (Linker Dom.) antibody
  Rabbit Polyclonal Anti-PAK6 Antibody (Linker Domain)  
PAK6 Rabbit Aff - Purified Hu P
50 µg / €425.00
  OriGene Technologies, Inc.

PAK6 antibody
  Rabbit Polyclonal Anti-PAK6 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using (PAK6 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

PAK6 (N-term) antibody
Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Aff - Purified Bov, Bt, Can, Chk, Elephant, Eq, Hu, Mky, Ms, Platypus, Rb, Rt E, P
50 µg / €425.00
  OriGene Technologies GmbH

PAK6 antibody
Western blot analysis of anti-PAK6 Pab in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK6 (arrow) was detected using purified Pab. Rabbit Ig Purified Hu IP, WB
0.4 ml / €415.00
  OriGene Technologies GmbH

PAK6 pSer602/560 antibody
Western blot analysis of extracts from HeLa cells (Lane 2), using PAK5/6 (Phospho-Ser602/Ser560) Antibody AP55829PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €300.00
  OriGene Technologies GmbH

PAK6 pSer602/560 antibody
Western blot analysis of extracts from HeLa cells (Lane 2), using PAK5/6 (Phospho-Ser602/Ser560) Antibody AP55829PU-N. The lane on the left is treated with antigen-specific peptide. Rabbit Aff - Purified Hu, Ms WB
50 µg / €230.00
  OriGene Technologies GmbH

CRISPR

Catalog No. Species Donor Vector  

PAK6 - human gene knockout kit via CRISPR
PAK6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAK6 - human gene knockout kit via CRISPR
PAK6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAK6 - human gene knockout kit via CRISPR
PAK6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PAK6 - human gene knockout kit via CRISPR
PAK6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PAK6 (transcript variant 1)
  Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, 10 µg  
PAK6 Human > 90 %
Preparation: .
Purity Detail: >90% as determined by SDS-PAGE and Coomassie blue staining.		 E. coli
10 µg / €240.00
  OriGene Technologies, Inc.

PAK6 (transcript variant 1)
  Purified recombinant kinase domain protein of human p21 protein (Cdc42/Rac)-activated kinase 6 (PAK6), transcript variant 1, 100 µg  
PAK6 Human > 90 %
Preparation: .
Purity Detail: >90% as determined by SDS-PAGE and Coomassie blue staining.		 E. coli
0.1 mg / €1,320.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pak6 (GFP-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Pak6 (GFP-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,440.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Pak6 (GFP-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Pak6 (GFP-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,440.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Pak6 (Myc-DDK-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Pak6 (Myc-DDK-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,290.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Pak6 (Myc-DDK-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, Pak6 (Myc-DDK-tagged) - Mouse p21 protein (Cdc42/Rac)-activated kinase 6 (Pak6), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,290.00
  OriGene Technologies, Inc.
 

19 Item(s)

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19 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. CRISPR (4)
  2. Mouse Lenti ORF Particle (4)
  3. Primary Antibody (9)
  4. Protein | Growth Factor (2)
Clonality
  1. Polyclonal (9)
Target
  1. PAK6 (11)
Property
  1. Center (1)
  2. Linker Dom. (1)
  3. N-term (1)
  4. pSer602/560 (2)
Reactivity
  1. Human (Hu) (9)
  2. Mouse (Ms) (4)
  3. Bovine (Bov) (1)
  4. Bat (Bt) (1)
  5. Canine (Can) (1)
  6. Chicken (Chk) (1)
  7. Elephant (1)
  8. Equine (Eq) (1)
  9. Monkey (Mky) (1)
  10. Platypus (1)
  11. Rabbit (Rb) (1)
  12. Rat (Rt) (1)
Applications
  1. Paraffin Sections (P) (6)
  2. Western blot / Immunoblot (WB) (5)
  3. Enzyme Immunoassay (E) (3)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  5. Immunoprecipitation (IP) (1)
Presentation
  1. Aff - Purified (7)
  2. Purified (2)
Host
  1. Rabbit (9)
Images
  1. 1 image (9)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Immunofluorescence (IF) (2)
  3. IHC (2)
  4. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (2)
Source
  1. E. coli (2)
Species (CRISPR)
  1. Human (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. OriGene Technologies (19)
Service
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  • fax: +49-5221-34606-11
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