PAM antibody
Principal name
PAM antibody
Alternative names for PAM antibody
PHM, PAL, Peptidyl-glycine alpha-amidating monooxygenase, Peptidylglycine alpha-hydroxylating monooxygenase, Peptidyl-alpha-hydroxyglycine alpha-amidating lyase
Ncbi ID
9606, NP_000910, NM_138821, NM_000919, NP_620176, NP_000910.2, NP_038654.2, NM_013626, NM_013000, NM_138766, NM_138822, NM_001177306
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB)
Background of PAM antibody
PAM is a multifunctiol protein. It has two enzymatically active domains with catalytic activities-peptidylglycine alpha-hydroxylating monooxygese (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products.This gene encodes a multifunctiol protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygese (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple altertively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
General readings
Glauder J, Ragg H, Rauch J, Engels JW.
Human peptidylglycine alpha-amidating monooxygenase: cDNA, cloning and functional expression of a truncated form in COS cells.
Biochem Biophys Res Commun. 1990 Jun 15;169(2):551-8.
PMID: 2357221
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA303337 | PAM (C-term) antibody |
||||||
| Goat Polyclonal Antibody against PAM | |||||||
 |
Goat | Aff - Purified | Hu | WB |
0.1 mg /
€360.00
|
||
| OriGene Technologies, Inc. | |||||||
CRISPR
| Catalog No. | Species | Donor Vector | |
|---|---|---|---|
| KN202074 | PAM - human gene knockout kit via CRISPR |
||
 |
Human | GFP-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN202074BN | PAM - human gene knockout kit via CRISPR |
||
|
Human | mBFP-Neo |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN202074LP | PAM - human gene knockout kit via CRISPR |
||
|
Human | Luciferase-Puro |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
| KN202074RB | PAM - human gene knockout kit via CRISPR |
||
|
Human | RFP-BSD |
1 kit /
€1,290.00
|
| OriGene Technologies, Inc. | |||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP302074 | PAM (transcript variant 3) |
||||
| Recombinant protein of human peptidylglycine alpha-amidating monooxygenase (PAM), transcript variant 3 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
 +1 additional image |
|||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY408466 | PAM overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. | ||
| LY424457 | PAM overexpression lysate |
|
|
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC212581L2V | Lenti ORF particles, PAM (mGFP-tagged)-Human peptidylglycine alpha-amidating monooxygenase (PAM), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,130.00
|
|
| OriGene Technologies, Inc. | ||
| RC213661L2V | Lenti ORF particles, PAM (mGFP-tagged)-Human peptidylglycine alpha-amidating monooxygenase (PAM), transcript variant 2, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,010.00
|
|
| OriGene Technologies, Inc. | ||
| RC230597L2V | Lenti ORF particles, PAM (mGFP-tagged)-Human peptidylglycine alpha-amidating monooxygenase (PAM), transcript variant 5, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,120.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR202803L2V | Lenti ORF particles, Pam (GFP-tagged ORF) - Rat peptidylglycine alpha-amidating monooxygenase (Pam), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,860.00
|
|
| OriGene Technologies, Inc. | ||
| RR202803L1V | Lenti ORF particles, Pam (Myc-DDK-tagged ORF) - Rat peptidylglycine alpha-amidating monooxygenase (Pam), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,670.00
|
|
| OriGene Technologies, Inc. | ||