PCDHA7 antibody
Principal name
PCDHA7 antibody
Alternative names for PCDHA7 antibody
Protocadherin alpha-7, PCDH-alpha-7, CNRS4
SwissProt ID
Q9UN72 (Human)
Gene ID
56141 (PCDHA7)
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of PCDHA7 antibody
The PCDHA7 gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
General readings
Wu, C., et al. Proteomics 7(11):1775-1785 (2007)
Wu, Q., et al. Genome Res. 11(3):389-404 (2001)
Nollet, F., et al. J. Mol. Biol. 299(3):551-572 (2000)
Yagi, T., et al. Genes Dev. 14(10):1169-1180 (2000)
Wu, Q., et al. Proc. Natl. Acad. Sci. U.S.A. 97(7):3124-3129 (2000)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP53201PU-N | PCDHA7 (Center) antibody |
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 |
Rabbit | Ig | Aff - Purified | Hu | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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Lysates
| Catalog No. | ||
|---|---|---|
| LY412922 | PCDHA7 overexpression lysate |
|
 |
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC221616L2V | Lenti ORF particles, PCDHA7 (mGFP-tagged) - Human protocadherin alpha 7 (PCDHA7), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,060.00
|
|
| OriGene Technologies, Inc. | ||