Switch to Europe/Worldwide website Switch to German website Switch to French website Switch to OriGene Technologies, Inc. (North America)
Home » Target » PDZD1 antibody

PDZD1 antibody

(reset)

Principal name

PDZD1 antibody

Alternative names for PDZD1 antibody

PDZK1, NHERF3, NHERF-3, NHE-RF3, NaPi-Cap1, CAP70, PDZ domain-containing protein 1, Na(+)/H(+) exchange regulatory cofactor NHE-RF3, Sodium-hydrogen exchanger regulatory factor 3

SwissProt ID

Q3T0X8 (Bovin), Q5T2W1 (Human), Q865P3 (Rabit), Q9JIL4 (Mouse), Q9JJ40 (Rat)

Gene ID

5174 (PDZK1), 59020 (Pdzk1), 65144

Ncbi ID

9606, NP_002605, NP_001188254.1, NP_001188254, NM_002614, NP_001139473.1, NM_001146001, NM_031712, NM_021517

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of PDZD1 antibody

Scaffold or adaptor proteins recruits and/or anchor their binding partners to specific subcellular locations, serving as a platform to regulate interactions between proteins involved in diverse sigl transduction pathways, and PDZK1 (PDZ domain-containing protein 1) is a scaffold protein belonging to NHERFs family. PDZK1 expression is largely limited to epithelial cells and is mainly expressed in rel proximal epithelial cells, hepatocytes, and at a lower level in other epithelial as well as certain endothelial cells. PDZK1 has four PDZ domains which facilitates its interaction with its binding partners, including ion transporters (e.g. CFTR, OCTN1/OCTN2 etc) and several GPCRs (e.g. HTR2B, SSTR family members). Through its interaction with HDL and SR-BI, PDZK1 can play role in reverse cholesterol transport and for HDL-mediated vascular re-endothelialisation. When complex with SLC9A3R1, PDZK1 cluster proteins that are functiolly dependent in a mutual fashion and modulate the trafficking as well as the activity of associated membrane proteins. PDZK1 plays a role in cellular mechanisms associated with multidrug resistance through its interaction with ABCC2 and PDZK1IP1. PDZK1 also implicates in connecting SCARB1 with cellular machineries for intracellular cholesterol transport and/or metabolism and regulation of proximal tubular +-dependent inorganic phosphate cotransport.

General readings

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
LaLonde, D.P., et al. Mol. Biol. Cell 21(9):1519-1529(2010)
Polasek, O., et al. Croat. Med. J. 51(1):32-39(2010)
Gunjaca, G., et al. Croat. Med. J. 51(1):23-31(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

H00005174-M01 - PDZD1
Immunoperoxidase of monoclonal antibody to PDZK1 on formalin-fixed paraffin-embedded human transitional cell carcinoma tissue. [antibody concentration 5ug/ml]
H00005174-M01 - PDZD1
PDZK1 monoclonal antibody (M01), clone 1C3-2B11. Western Blot analysis of PDZK1 expression in human kidney.
H00005174-M01 - PDZD1
Detection limit for recombinant GST tagged PDZK1 is approximately 0.03ng/ml as a capture antibody.
H00005174-M01A - PDZD1
PDZK1 monoclonal antibody (M01), clone 1C3-2B11. Western Blot analysis of PDZK1 expression in human kidney.
ARP41505_P050 - PDZD1
Human 293T; WB Suggested Anti-PDZK1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: 293T cell lysate; PDZK1 antibody - N-terminal region (ARP41505_P050) in Human 293T cells using Western Blot
ARP41506_P050 - PDZD1
Human HepG2; WB Suggested Anti-PDZK1 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: HepG2 cell lysate. PDZK1 is supported by BioGPS gene expression data to be expressed in HepG2.; PDZK1 antibody - N-terminal region (ARP41506_P050) in Human HepG2 cells using Western Blot
AM31814PU-N - PDZD1
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
AM31814PU-N - PDZD1
PDZK1 monoclonal antibody AM31814PU-N. Western Blot analysis of PDZK1 expression in human kidney.
AM31814PU-N - PDZD1
Detection limit for recombinant GST tagged PDZK1 is approximately 0.03ng/ml as a capture antibody.
AP53250PU-N - PDZD1
Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with PDZK1 Antibody (Center) Cat.-No AP53250PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.
AP53250PU-N - PDZD1
Western blot analysis of PDZK1 Antibody (Center) Cat.-No AP53250PU-N in NCI-H292 cell line lysates (35ug/lane). This demonstrates the PDZK1 antibody detected the PDZK1 protein (arrow).
AR50899PU-N - PDZD1
AM50029PU-N - PDZD1
The cell lysates of HeLa (40ug) and 293T (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDZK1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
TP300444 - PDZD1
TA332609 - PDZD1
Western blot analysis of extracts of various cell lines, using PDZK1 antibody.
TA336647 - PDZD1
Western Blot: PDZK1 Antibody [TA336647] - WB analysis of PDZK1 in fetal human liver lysate.
TA336647 - PDZD1
Immunohistochemistry: PDZK1 Antibody [TA336647] - IHC analysis of PDZK1 in mouse kidney using DAB with hematoxylin counterstain.
TA336647 - PDZD1
Immunocytochemistry/Immunofluorescence: PDZK1 Antibody [TA336647] - PDZK1 antibody was tested in HeLa cells with FITC (green). Nuclei and alpha-tubulin were counterstained with Dapi (blue) and Dylight 550 (red).
TA346092 - PDZD1
WB Suggested Anti-PDZK1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysatePDZK1 is supported by BioGPS gene expression data to be expressed in HepG2
TA346091 - PDZD1
WB Suggested Anti-PDZK1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: 293T cell lysate

11 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PDZD1 antibody
  Rabbit anti-PDZK1 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using PDZK1 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €335.00
  OriGene Technologies, Inc.

PDZD1 antibody
  Rabbit Polyclonal PDZK1 Antibody  
Western Blot: PDZK1 Antibody [TA336647] - WB analysis of PDZK1 in fetal human liver lysate. Rabbit Purified Bov, Hu, Ms C, ICC/IF, P, WB
0.1 ml / €395.00
  OriGene Technologies, Inc.
+2 additional images

PDZD1 (1-520) antibody
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 1C3-2B11 Purified Hu E, P, WB
50 µg / €475.00
  OriGene Technologies GmbH
+2 additional images

PDZD1 antibody
The cell lysates of HeLa (40ug) and 293T (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDZK1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b AT1A2 Purified Hu E, WB
0.1 ml / €330.00
  OriGene Technologies GmbH

PDZD1 antibody
The cell lysates of HeLa (40ug) and 293T (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PDZK1 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2b AT1A2 Purified Hu E, WB
50 µl / €220.00
  OriGene Technologies GmbH

PDZD1 (Center) antibody
Immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue reacted with PDZK1 Antibody (Center) Cat.-No AP53250PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €415.00
  OriGene Technologies GmbH
+1 additional image

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PDZD1
  Recombinant protein of human PDZ domain containing 1 (PDZK1)  
PDZD1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.
 

Lysates

Catalog No.    

PDZK1 overexpression lysate
PDZK1 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pdzk1 (GFP-tagged) - Mouse PDZ domain containing 1 (Pdzk1), transcript variant 1, 200 uL, >10^7 TU/mL
Lenti ORF particles, Pdzk1 (GFP-tagged) - Mouse PDZ domain containing 1 (Pdzk1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,210.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Pdzk1 (GFP-tagged ORF) - Rat PDZ domain containing 1 (Pdzk1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Pdzk1 (GFP-tagged ORF) - Rat PDZ domain containing 1 (Pdzk1), 200 uL, >10^7 TU/mL  
200 µl / €1,220.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Pdzk1 (Myc-DDK-tagged ORF) - Rat PDZ domain containing 1 (Pdzk1), 200 uL, >10^7 TU/mL
Lenti ORF particles, Pdzk1 (Myc-DDK-tagged ORF) - Rat PDZ domain containing 1 (Pdzk1), 200 uL, >10^7 TU/mL  
200 µl / €1,090.00
  OriGene Technologies, Inc.
 

11 Item(s)

per page
11 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Lysate (1)
  2. Mouse Lenti ORF Particle (1)
  3. Primary Antibody (6)
  4. Protein | Growth Factor (1)
  5. Rat Lenti ORF Particle (2)
Clonality
  1. Monoclonal (3)
  2. Polyclonal (3)
Target
  1. PDZD1 (7)
Property
  1. 1-520 (1)
  2. Center (1)
Reactivity
  1. Human (Hu) (6)
  2. Mouse (Ms) (2)
  3. Bovine (Bov) (1)
  4. Rat (Rt) (1)
Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Enzyme Immunoassay (E) (3)
  3. Paraffin Sections (P) (3)
  4. Frozen sections (C) (1)
  5. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Purified (5)
  2. Aff - Purified (1)
Host
  1. Mouse (3)
  2. Rabbit (3)
Images
  1. 1 image (7)
  2. 3+ images (2)
Images: Applications
  1. Western blot / Immunoblot (WB) (6)
  2. Paraffin Sections (P) (2)
  3. ELISA (capture) (E(capture)) (1)
  4. Immunofluorescence (IF) (1)
  5. IHC (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (11)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
© Copyright 1998 - 2018 OriGene Technologies GmbH
  • LinkedIn