PI4K2A antibody
Principal name
PI4K2A antibody
Alternative names for PI4K2A antibody
Phosphatidylinositol 4-kinase type 2-alpha, Phosphatidylinositol 4-kinase type II-alpha
Ncbi ID
9606, NP_060895.1, NM_018425, NP_060895, NP_663476.1, BC022127, NM_145501, NM_053735
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)
Background of PI4K2A antibody
Phosphatidylinositolpolyphosphates (PtdInsPs) are centrally involved in many biologic processes, ranging from cell growth and organization of the actin cytoskeleton to endo- and exocytosis. PI4KII phosphorylates PtdIns at the D-4 position, an essential step in the biosynthesis of PtdInsPs. PI4K II is activated by detergent and inhibited by adenosine. Overexpression of PI4KII in COS-7 cells increases synthesis of PtdIns4P. Some cells overexpressing PI4KII have scattered or no perinuclear Golgi. Knockdown of PI4KII by RNA interference (RNAi) does not disrupt the Golgi, and some cells show expanded Golgi. RNAi reduces the Golgi level of PtdIns4P and blocks the association between AP1 and the trans-Golgi network. PI4KII RNAi had little effect on intra-Golgi trafficking, but it inhibited export to plasma membrane export by 35%. It has been proposed that PI4KII generates PtdIns4P-rich domains within the Golgi that specify docking of the AP1 coat machinery.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| AP14956PU-N | PI4K2A (N-term) antibody |
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 |
Rabbit | Ig | Purified | Hu | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
 +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP301367 | PI4K2A |
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| Recombinant protein of human phosphatidylinositol 4-kinase type 2 alpha (PI4K2A) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY413054 | PI4K2A overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR207674L2V | Lenti ORF particles, Pi4k2a (GFP-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,240.00
|
|
| OriGene Technologies, Inc. | ||
| MR207675L2V | Lenti ORF particles, Pi4k2a (GFP-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,170.00
|
|
| OriGene Technologies, Inc. | ||
| MR207674L1V | Lenti ORF particles, Pi4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (cDNA clone MGC:37783 IMAGE:5097465), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,110.00
|
|
| OriGene Technologies, Inc. | ||
| MR207675L1V | Lenti ORF particles, Pi4k2a (Myc-DDK-tagged) - Mouse phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,040.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR210079L2V | Lenti ORF particles, Pi4k2a (GFP-tagged ORF) - Rat phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,160.00
|
|
| OriGene Technologies, Inc. | ||
| RR210079L1V | Lenti ORF particles, Pi4k2a (Myc-DDK-tagged ORF) - Rat phosphatidylinositol 4-kinase type 2 alpha (Pi4k2a), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,040.00
|
|
| OriGene Technologies, Inc. | ||