PIGT antibody

Principal name

PIGT antibody

Alternative names for PIGT antibody

PIG-T, GPI transamidase component PIG-T, CGI-06, PSEC0, Phosphatidylinositol-glycan biosynthesis class T protein

SwissProt ID

Q8BXQ2 (Mouse), Q969N2 (Human), Q9Y2Z5 (Human)

Gene ID

51604 (PIGT), 78928 (Pigt)

Available reactivities

Hu (Human), Can (Canine), Ms (Mouse), Rt (Rat), African clawed frog, Bov (Bovine), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB)

Background of PIGT antibody

PIGT is a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Li, H.L. et al., FEBS Lett. 580(7): 1723-1728 (2006)
Vainauskas, S. et al., J. Biol. Chem. 280(16): 16402-16409 (2005)
Ohishi, K. et al., J. Biol. Chem. 278(16): 13959-13967 (2003)
Eisenhaber, B. et al., Bioessays 25(4): 367-385 (2003)
Vainauskas, S. et al., J. Biol. Chem. 277(34): 30535-30542 (2002)

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