PIGZ antibody

Principal name

PIGZ antibody

Alternative names for PIGZ antibody

PIG-Z, GPI mannosyltransferase 4, GPI-MT-IV, SMP3, Phosphatidylinositol-glycan biosynthesis class Z protein

SwissProt ID

Q86VD9 (Human), Q8BTP0 (Mouse), Q8MT80 (Drome)

Gene ID

80235 (PIGZ)

Available reactivities

Bov (Bovine), Can (Canine), Dros (Drosophila), Hu (Human), Ms (Mouse), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Rt (Rat), Ye (Yeast)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB)

Background of PIGZ antibody

The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. PIGZ is a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.The glycosylphosphatidylinositol (GPI) anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. This gene encodes a protein that is localized to the endoplasmic reticulum, and is involved in GPI anchor biosynthesis. As shown for the yeast homolog, which is a member of a family of dolichol-phosphate-mannose (Dol-P-Man)-dependent mannosyltransferases, this protein can also add a side-branching fourth mannose to GPI precursors during the assembly of GPI anchors.

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