PKDREJ antibody
Principal name
PKDREJ antibody
Alternative names for PKDREJ antibody
PKD and REJ homolog, Polycystic kidney disease and receptor for egg jelly-related protein
Gene ID
10343 (PKDREJ)
Ncbi ID
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Paraffin Sections (P), Western blot / Immunoblot (WB)
Background of PKDREJ antibody
This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined.; FUNCTION: May have a central role in fertilization. May generate a Ca(2+) transporting channel directly involved in initiating the acrosome reaction of the sperm. SUBUNIT: May form homomultimers or heteromultimers in combination with an as yet unidentified subunits. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.; TISSUE SPECIFICITY: Exclusively expressed in testis.
General readings
Hamm,D., (2007) Am. J. Hum. Genet. 81 (1), 44-52
