PLA2G2A antibody
Principal name
PLA2G2A antibody
Alternative names for PLA2G2A antibody
PLA2B, PLA2L, RASF-A, NPS-PLA2, Group IIA phospholipase A2, Phospholipase A2 membrane associated, Phosphatidylcholine 2-acylhydrolase 2A, Non-pancreatic secretory phospholipase A2
SwissProt ID
P14422 (Rabit), P14423 (Rat), P14555 (Human), P31482 (Mouse), P47711 (Cavpo), Q56JZ2 (Bovin)
Ncbi ID
NP_000291, 9606, AAH05919.1, NP_000291.1, NP_001076000.1, NM_001082531, NM_031598
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB)
Background of PLA2G2A antibody
Phospholipase A2 (PLA2) catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to liberate arachidonic acid (AA), a precursor of eicosanoids including prostaglandins and leukotrienes. The same reaction also produces lysophosholipids, which represent another class of lipid mediators. The secretory PLA2 (sPLA2) family, in which 10 isozymes have been identified, consists of low-molecular weight, Ca2+-requiring secretory enzymes that have been implicated in a number of biological processes, such as modification of eicosanoid generation, inflammation, and host defense. This enzyme has been proposed to hydrolyze phosphatidylcholine (PC) in lipoproteins to liberate lyso-PC and free fatty acids in the arterial wall, thereby facilitating the accumulation of bioactive lipids and modified lipoproteins in atherosclerotic foci. In mice, sPLA2 expression significantly influences HDL particle size and composition and demonstrate that an induction of sPLA2 is required for the decrease in plasma HDL cholesterol in response to inflammatory stimuli. Instillation of bacteria into the bronchi was associated with surfactant degradation and a decrease in large:small ratio of surfactant aggregates in rats.
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA323702 | PLA2G2A antibody |
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| Anti-PLA2G2A Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA348949 | PLA2G2A antibody |
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| Goat Polyclonal Anti-PLA2G2A Antibody | |||||||
 |
Goat | Purified | Hu | WB |
0.1 mg /
€360.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA808040 | PLA2G2A antibody |
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| PLA2G2A mouse monoclonal antibody, clone OTI1C2 (formerly 1C2) | |||||||
 |
Mouse | IgG1 | OTI1C2 | Purified | Hu | WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
|
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP303250 | PLA2G2A |
||||
| Recombinant protein of human phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A) | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
| PA521X | PLA2G2A (His-tagged Fusion Protein) |
||||
 |
Human | Purified | > 95 % >95% | E. coli |
0.1 mg /
€490.00
|
| OriGene Technologies GmbH | |||||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR200976L2V | Lenti ORF particles, Pla2g2a (GFP-tagged) - Mouse phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), 200 uL, >10^7 TU/mL |
|
 |
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR200976L1V | Lenti ORF particles, Pla2g2a (Myc-DDK-tagged) - Mouse phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR211265L2V | Lenti ORF particles, Pla2g2a (GFP-tagged ORF) - Rat phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR211265L1V | Lenti ORF particles, Pla2g2a (Myc-DDK-tagged ORF) - Rat phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||