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PLCB3 antibody

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Principal name

PLCB3 antibody

Alternative names for PLCB3 antibody

PLC-beta-3, Phospholipase C-beta-3, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-3, Phosphoinositide phospholipase C-beta-3

SwissProt ID

P51432 (Mouse), Q01970 (Human), Q99JE6 (Rat)

Gene ID

5331 (PLCB3)

Ncbi ID

NP_000923, NP_000923.1

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)

Background of PLCB3 antibody

Phosphoinositide-specific phospholipase C (PLC) plays a critical role in the initiation of receptor mediated signal transduction through the generation of the two second messengers, inositol 1, 4, 5-triphosphate and diacylglycerol from phosphatidylinositol 4, 5 bisphosphate. A total of eight mammalian PLC isozymes have been described (PLC β1, PLC β2, PLC β3, PLC β4, PLC γ1, PLC γ2, PLC δ1 and PLC δ2) with molecular weights ranging from 85 to 150 kDa. The γ-type enzymes are unique in that they contain SH2 and SH3 domains. Moreover, the two γ-type enzymes, but not the β and δ isozymes, are subject to activation by a number of protein tyrosine kinases which associate with their SH2 domains and induce their activation by phosphoryation. In contrast, activation of PLC β1, PLC β2 and PLC β3 is mediated by the α subunits of the Gq class of heterotrimeric G proteins and by certain βγ G protein subunits. The regulatory mechanisms for PLC δ1 and PLC δ2 are as yet not resolved.

AP20281PU-N - PLCB3
Immunohistochemistry analyzes of PLC β3 antibody (AP20281PU-N) in paraffin-embedded human brain tissue.
AP20281PU-N - PLCB3
Western blot analysis of PLC β3 antibody (AP20281PU-N) in extracts from HeLa cells.
AP20327PU-N - PLCB3
Immunohistochemistry analyzes of PLC β3 antibody (Cat.-No.: AP20327PU-N) in paraffin-embedded human breast carcinoma tissue.
A0078-1 - PLCB3
Immunohistochemistry analysis of paraffin-embedded human brain, using PLCB3 (Phospho-Ser1105) Antibody. The picture on the right is treated with the synthesized peptide.
A0078-1 - PLCB3
Western blot analysis of extracts from A431 cells, using PLCB3 (Phospho-Ser1105) Antibody. The lane on the right is treated with the synthesized peptide.
A0722-1 - PLCB3
Immunohistochemistry analysis of paraffin-embedded human brain, using PLC beta3 (Phospho-Ser537) Antibody. The picture on the right is treated with the synthesized peptide.
A0722-1 - PLCB3
Western blot analysis of extracts from Jurkat cells treated with UV 15', using PLC beta3 (Phospho-Ser537) Antibody. The lane on the right is treated with the synthesized peptide.
B0078-1 - PLCB3
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PLCB3 (Ab-1105) Antibody. The picture on the right is treated with the synthesized peptide.
B0078-1 - PLCB3
Western blot analysis of extracts from HeLa cells, treated with PMA 125ng/ml 30', using PLCB3 (Ab-1105) Antibody. The lane on the right is treated with the synthesized peptide.
B0722-1 - PLCB3
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using PLC beta3 (Ab-537) Antibody. The picture on the right is treated with the synthesized peptide.
CPA1895-100ul - PLCB3
Western blot analysis of PLC beta 3 (pS537) expression in HeLa PMA-treated (A); MCF7 UV-treated (B); mouse brain (C); rat brain (D) whole cell lysates.
TA314347 - PLCB3
Western blot analysis of extracts from A431 cells, using PLC-ß (phospho-Ser1105) antibody.The lane on the right is treated with the synthesized peptide.
TA314347 - PLCB3
Immunohistochemical analysis of paraffin-embedded human brain tissue using PLC-ß (phospho-Ser1105) antibody.The picture on the right is treated with the synthesized peptide.

4 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PLCB3 antibody
  Rabbit polyclonal PLC-beta (Ser1105) antibody(Phospho-specific)  
Western blot analysis of extracts from A431 cells, using PLC-ß (phospho-Ser1105) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

PLCB3 antibody
  Rabbit Polyclonal Anti-PLCB3 Antibody  
PLCB3 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

PLCB3 antibody
Immunohistochemistry analyzes of PLC β3 antibody (AP20281PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

PLCB3 antibody
Immunohistochemistry analyzes of PLC β3 antibody (Cat.-No.: AP20327PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P
0.1 mg / €370.00
  OriGene Technologies GmbH

4 Item(s)

per page

Available Filters

Product Type
  1. Primary Antibody (4)
Clonality
  1. Polyclonal (4)
Target
  1. PLCB3 (4)
Reactivity
  1. Human (Hu) (4)
  2. Mouse (Ms) (4)
  3. Rat (Rt) (4)
Applications
  1. Paraffin Sections (P) (4)
  2. Western blot / Immunoblot (WB) (3)
  3. Enzyme Immunoassay (E) (2)
  4. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Aff - Purified (2)
  2. Purified (2)
Host
  1. Rabbit (4)
Images
  1. 1 image (3)
Images: Applications
  1. Paraffin Sections (P) (2)
  2. Western blot / Immunoblot (WB) (2)
  3. IHC (1)
Manufacturer
  1. OriGene Technologies (4)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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