Plexin A2 antibody

Background of Plexin A2 antibody

PLX2 is a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular sigl transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce sigls from semaphorin-3A and -3C. This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular sigl transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce sigls from semaphorin-3A and -3C.