PMS2CL antibody

Principal name

PMS2CL antibody

Alternative names for PMS2CL antibody

PMS2-C terminal-like protein

SwissProt ID

Q68D20 (Human)

Gene ID

441194 (PMS2CL)

Ncbi ID

9606

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P)

Background of PMS2CL antibody

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

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