POGZ antibody
Principal name
POGZ antibody
Alternative names for POGZ antibody
KIAA0461, SUHW5, ZNF280E, ZNF635, Pogo transposable element with ZNF domain, Suppressor of hairy wing homolog 5
Ncbi ID
NP_055915, 9606, 10090, NP_766271.2, NP_665739, NM_015100, NP_001181866.1, NM_001165948, NM_207171, NM_145796, NM_001194938, NM_001194937
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E)
Background of POGZ antibody
Pogz is a zinc-finger protein containing at least 8 C2H2 zinc fingers, a CENP-B (centromere protein-B) domain, and a DDE domain found in the bacterial transposase/retroviral integrase family. Members of this family of integrases share structural homologies and show similar catalytic activity to the RAG1 and RAG2 proteins that initiate V(D)J recombination in lymphoid progenitors. Mouse Pogz has a human homolog with a base pair similarity of 90% and amino acid similarity of 93% for the full length protein. In humans at least 3 variants have been predicted and they are all similar at the N-terminus. A number of expressed sequence tags (ESTAs) cloned from murine undifferentiated ES cells and Lin-/c-Kit+/Sca-1+ hematopoietic stem cell cDNA libraries correspond to the Pogz gene, further underlining an important function for this gene in stem cells. In mice, deletion of the gene in all tissues early in embryogenesis has been shown to be lethal.
General readings
Beausoleil,S.A., (2004) Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA319377 | POGZ antibody |
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| Rabbit polyclonal anti-Pogz antibody | |||||||
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Rabbit | IgG | Aff - Purified | Can, Cattle, Chimp, Chk, Hu, Macaque, Ms, olive Baboon, Rt | E, WB |
0.1 mg /
€515.00
|
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| OriGene Technologies, Inc. | |||||||
