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POLA1 antibody

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Principal name

POLA1 antibody

Alternative names for POLA1 antibody

DNA polymerase alpha catalytic subunit, DNA polymerase alpha catalytic subunit p180

SwissProt ID

O89042 (Rat), P09884 (Human), P33609 (Mouse), Q9DE46 (Xenla)

Gene ID

5422 (POLA1), 18968 (Pola1)

Ncbi ID

9606, NP_058633, NP_058633.2, NM_008892, NM_016937, NP_032918.1

Available reactivities

Hu (Human)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Frozen Sections (C), Immunoprecipitation (IP)

Background of POLA1 antibody

DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, these enzymes are involved in the processing of Okazaki fragments, whereas in DNA repair they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases. DNA pol α, β, δ and ε are involved in DNA replication and repair. DNA pol δ and DNA pol ε are multisubunit enzymes, with DNA pol δ consisting of two subunits: p125, which interacts with the sliding DNA clamp protein PCNA; and p50. The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA. DNA pol ζ is ubiquitously expressed in various tissues and mediates the cellular mechanism of damage-induced mutagenesis. DNA pol θ is a DNA polymerase-helicase that binds ATP and is involved in the repair of interstrand crosslinks.

H00005422-M01 - POLA1
POLA monoclonal antibody (M01), clone 3C11 Western Blot analysis of POLA expression in HeLa NE ( Cat # L013V3 ).
H00005422-M01 - POLA1
Detection limit for recombinant GST tagged POLA is approximately 0.3ng/ml as a capture antibody.
AP06662PU-N - POLA1
Western blot (WB) analysis of DNA pol α antibody (Cat.-No.: AP06662PU-N) in extracts from A549 cells.
C10322-1 - POLA1
Western blot analysis of extracts from HepG2/293/Jurkat cells, using DNA Polymerase alpha Antibody. The lane on the right is treated with the synthesized peptide.
AM26670PU-S - POLA1
Immunocytochemical detection of DNA polymerase alpha on aceton fixed HEp-II with AM26670PU-S
AM26670PU-S - POLA1
Flow cytometric analysis of DNA polymerase alpha expression in Jurkat cells. Dot line histogram indicates the reaction of isotypic control to the cells. Solid line histogram indicates the reaction of AM26670PU-S to the cells.
CPA1906-100ul - POLA1
Western blot analysis of DNA Polymerase alpha 1 expression in A549 (A); A431 (B); HeLa (C) whole cell lysates.
TA314358 - POLA1
Western blot analysis of extracts from Jurkat cells, 293 cells and HepG2 cells, using DNA Polymerase a antibody.The lane on the right is treated with the synthesized peptide.
TA347928 - POLA1
Western blot analysis of DNA Polymerase a expression in 293 cells
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLA1 antibody
Immunocytochemical detection of DNA polymerase alpha on aceton fixed HEp-II with AM26670PU-S Mouse IgG1 CL22-2-42B Purified Hu C, F, ICC/IF
50 µg / €395.00
  OriGene Technologies GmbH
+1 additional image

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POLA1 antibody
  Rabbit polyclonal DNA Polymerase a antibody  
Western blot analysis of extracts from Jurkat cells, 293 cells and HepG2 cells, using DNA Polymerase a antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

POLA1 antibody
  Rabbit Polyclonal Anti-DNA Polymerase a Antibody  
Western blot analysis of DNA Polymerase a expression in 293 cells Rabbit IgG Purified Hu WB
0.1 mg / €335.00
  OriGene Technologies, Inc.

POLA1 antibody
Western blot (WB) analysis of DNA pol α antibody (Cat.-No.: AP06662PU-N) in extracts from A549 cells. Rabbit Aff - Purified Hu WB
0.1 mg / €370.00
  OriGene Technologies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, POLA1 (mGFP-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL
Lenti ORF particles, POLA1 (mGFP-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL  
200 µl / €2,680.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, POLA1 (Myc-DDK-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL
Lenti ORF particles, POLA1 (Myc-DDK-tagged)-Human polymerase (DNA directed), alpha 1, catalytic subunit (POLA1), 200 uL, >10^7 TU/mL  
200 µl / €2,420.00
  OriGene Technologies, Inc.
 

6 Item(s)

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Available Filters

Product Type
  1. Human Lenti ORF Particle (2)
  2. Primary Antibody (4)
Clonality
  1. Polyclonal (3)
  2. Monoclonal (1)
Target
  1. POLA1 (4)
Reactivity
  1. Human (Hu) (4)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Frozen sections (C) (1)
  3. Enzyme Immunoassay (E) (1)
  4. Flow cytometry (F) (1)
  5. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Purified (3)
  2. Aff - Purified (1)
Host
  1. Rabbit (3)
  2. Mouse (1)
Images
  1. 1 image (4)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Flow cytometry (F) (1)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Manufacturer
  1. OriGene Technologies (6)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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