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POLR3F antibody

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Principal name

POLR3F antibody

Alternative names for POLR3F antibody

RNA polymerase III subunit C6, RPC6, RPC39, DNA-directed RNA polymerase III subunit RPC6, DNA-directed RNA polymerase III subunit F, RNA polymerase III 39 kDa subunit

SwissProt ID

O94553 (Schpo), P32910 (Yeast), P91529 (Caeel), Q2T9S3 (Bovin), Q921X6 (Mouse), Q9H1D9 (Human), Q9VD25 (Drome)

Gene ID

10621 (POLR3F), 70408 (Polr3f)

Ncbi ID

9606, NP_006457, NP_006457.2, NM_006466, CAC11110, NP_084039.2

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Mky (Monkey), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of POLR3F antibody

The human POLR3F is a component of RNA III polymerase. RNA polymerase III transcribes many essential, small, noncoding RNAs, including the 5S rRNAs and tRNAs. While most pol III-transcribed genes are found scattered throughout the linear chromosome maps or in multiple linear clusters, there is increasing evidence that many of these genes prefer to be spatially clustered, often at or near the nucleolus. This association could create an environment that fosters the coregulation of transcription by pol III with transcription of the large ribosomal RNA repeats by RNA polymerase I (pol I) within the nucleolus. Given the high number of pol III-transcribed genes in all eukaryotic genomes, the spatial organization of these genes is likely to affect a large portion of the other genes in a genome. POLR3F has also been recently identified as an HIV dependency factor (HDF), suggesting that POLR3F may be an important drug target in HIV treatment. At least two isoforms of POLR3F are known to exist.

General readings

Chiu Y.-H., et al. (2009) Cell 138:576-591Ablasser A., et al. (2009) Nat. Immunol. 10:1065-1072

H00010621-B01P - POLR3F
Immunofluorescence of purified MaxPab antibody to POLR3F on HeLa cell. [antibody concentration 10 ug/ml]
H00010621-B01P - POLR3F
POLR3F MaxPab polyclonal antibody. Western Blot analysis of POLR3F expression in human pancreas.
H00010621-B01P - POLR3F
Western Blot analysis of POLR3F expression in transfected 293T cell line (H00010621-T01) by POLR3F MaxPab polyclonal antibody.Lane 1: POLR3F transfected lysate(34.76 KDa).Lane 2: Non-transfected lysate.
H00010621-B01P - POLR3F
POLR3F MaxPab polyclonal antibody. Western Blot analysis of POLR3F expression in HepG2.
ARP48705_P050 - POLR3F
Human 293T; Host:Rabbit. Target Name:POLR3F. Sample Tissue:Human 293T. Antibody Dilution: 1.0ug/ml. POLR3F is supported by BioGPS gene expression data to be expressed in HEK293T.; POLR3F antibody - middle region (ARP48705_P050) in Human 293T cells using Western Blot
ARP48705_P050 - POLR3F
Human 721_B; WB Suggested Anti-POLR3F Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: 721_B cell lysate. POLR3F is supported by BioGPS gene expression data to be expressed in 721_B.; POLR3F antibody - middle region (ARP48705_P050) in Human 721_B cells using Western Blot
ARP48704_P050 - POLR3F
Human PANC1; WB Suggested Anti-POLR3F Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: PANC1 cell lysate; POLR3F antibody - N-terminal region (ARP48704_P050) in Human PANC1 cells using Western Blot
AP23856PU-N - POLR3F
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
AP23856PU-N - POLR3F
Western blot analysis of POLR3F in human brain tissue lysate with POLR3F antibody at (A) 0.5 and (B) 1 µg/ml.
AR50721PU-N - POLR3F
CPA2497-100ul - POLR3F
Western blot analysis of POLR3F expression in HeLa (A); mouse liver (B); rat liver (C) whole cell lysates.
TA306617 - POLR3F
Western blot analysis of POLR3F in human brain tissue lysate with POLR3F antibody at (A) 0.5 and (B) 1 ug/ml.
TA306617 - POLR3F
Immunohistochemistry of POLR3F in human brain tissue with POLR3F antibody at 2.5 ug/ml.
TA306617 - POLR3F
Immunofluorescence of POLR3F in human brain tissue with POLR3F antibody at 20 ug/mL.
TA346754 - POLR3F
WB Suggested Anti-POLR3F Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: 721_B cell lysate.POLR3F is supported by BioGPS gene expression data to be expressed in 721_B
TA346754 - POLR3F
Host: Rabbit; Target Name: POLR3F; Sample Tissue: Human 293T; Antibody Dilution: 1.0 ug/ml.POLR3F is supported by BioGPS gene expression data to be expressed in HEK293T
TA346753 - POLR3F
WB Suggested Anti-POLR3F Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: PANC1 cell lysate

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

POLR3F antibody
  Rabbit Polyclonal POLR3F Antibody  
Western blot analysis of POLR3F in human brain tissue lysate with POLR3F antibody at (A) 0.5 and (B) 1 ug/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €415.00
  OriGene Technologies, Inc.
+2 additional images

POLR3F (N-term) antibody
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Purified Hu, Ms, Rt P, WB
50 µg / €425.00
  OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.    

POLR3F overexpression lysate
POLR3F overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

3 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Primary Antibody (2)
Clonality
  1. Polyclonal (2)
Target
  1. POLR3F (2)
Property
  1. N-term (1)
Reactivity
  1. Human (Hu) (2)
  2. Mouse (Ms) (2)
  3. Rat (Rt) (2)
Applications
  1. Paraffin Sections (P) (2)
  2. Western blot / Immunoblot (WB) (2)
  3. Enzyme Immunoassay (E) (1)
Presentation
  1. Aff - Purified (1)
  2. Purified (1)
Host
  1. Rabbit (2)
Images
  1. 1 image (2)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (2)
  2. Immunofluorescence (IF) (1)
  3. IHC (1)
  4. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (3)
Service
  • OriGene Technologies GmbH
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  • free call: 0800-227 47 46 (Germany only)
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