PPFIBP1 antibody
Principal name
PPFIBP1 antibody
Alternative names for PPFIBP1 antibody
Liprin-beta 1, SGT2, hSGT2, KIAA1230, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, PTPRF-interacting protein-binding protein 1
Ncbi ID
NP_803193, NP_001185844.1, NM_177444, NM_003622, NP_003613, NM_001170433
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Immunoprecipitation (IP)
Background of PPFIBP1 antibody
PPFIBP1 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis.The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
General readings
Kriajevska,M., (2002) J. Biol. Chem. 277 (7), 5229-5235
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP320285 | PPFIBP1 (transcript variant 1) |
||||
| Recombinant protein of human PTPRF interacting protein, binding protein 1 (liprin beta 1) (PPFIBP1), transcript variant 1 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€788.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY406168 | PPFIBP1 overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. | ||
| LY418540 | PPFIBP1 overexpression lysate |
|
|
0.1 mg /
€495.00
|
|
| OriGene Technologies, Inc. |
Human Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RC220285L2V | Lenti ORF particles, PPFIBP1 (mGFP-tagged) - Human PTPRF interacting protein, binding protein 1 (liprin beta 1) (PPFIBP1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€2,180.00
|
|
| OriGene Technologies, Inc. | ||
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR217335L2V | Lenti ORF particles, Ppfibp1 (GFP-tagged) - Mouse PTPRF interacting protein, binding protein 1 (liprin beta 1) (Ppfibp1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,870.00
|
|
| OriGene Technologies, Inc. | ||
| MR217335L1V | Lenti ORF particles, Ppfibp1 (Myc-DDK-tagged) - Mouse PTPRF interacting protein, binding protein 1 (liprin beta 1) (Ppfibp1), transcript variant 1, 200 uL, >10^7 TU/mL |
|
|
200 µl /
€1,680.00
|
|
| OriGene Technologies, Inc. | ||