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PRKAR2B antibody

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Principal name

PRKAR2B antibody

Alternative names for PRKAR2B antibody

PRKAR2, cAMP-dependent protein kinase type II-beta regulatory subunit

SwissProt ID

P12369 (Rat), P31322 (Bovin), P31323 (Human), P31324 (Mouse)

Gene ID

5577 (PRKAR2B), 282463, 19088 (Prkar2b), 24679

Ncbi ID

9606, 9913, NP_002727.2, 5874, NP_002727, NP_035288.2, NM_011158, NM_001030020, NM_002736

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of PRKAR2B antibody

cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. This subunit has been shown to interact with and suppress the transcriptional activity of the cAMP responsive element binding protein 1 (CREB1) in activated T cells. Knockout studies in mice suggest that this subunit may play an important role in regulating energy balance and adiposity. The studies also suggest that this subunit may mediate the gene induction and cataleptic behavior induced by haloperidol. [provided by RefSeq].

AP01453PU-N - PRKAR2B
Immunohistochemistry (IHC) analyzes of PKA IIβ reg antibody (Cat.-No.: AP01453PU-N) in paraffin-embedded human cervix carcinoma tissue.
AP01453PU-N - PRKAR2B
Western blot (WB) analysis of PKA IIβ reg antibody (Cat.-No.: AP01453PU-N) in extracts from Jurkat cells.
AP13605PU-N - PRKAR2B
Western blot analysis of anti-PRKAR2B Pab in mouse brain tissue lysate. PRKAR2B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
A0972-1 - PRKAR2B
Western blot analysis of extracts from COS7 cells treated with PMA 125ng/ml 30', using PKA-R2 beta (Phospho-Ser113) Antibody. The lane on the right is treated with the synthesized peptide.
B0972-1 - PRKAR2B
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using PKA-R2 beta (Ab-113) Antibody. The picture on the right is treated with the synthesized peptide.
B0972-1 - PRKAR2B
Western blot analysis of extracts from K562/HepG2 cells, using PKA-R2 beta (Ab-113) Antibody. The lane on the right is treated with the synthesized peptide.
AP53444PU-N - PRKAR2B
Western blot analysis of PRKAR2B (arrow) using rabbit polyclonal PRKAR2B Antibody (Center) (Cat. #AP53444PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRKAR2B gene.
AP55723PU-S - PRKAR2B
Western blot analysis of extracts from COS-7 cells treated with PMA using PKA-R2β (Phospho-Ser113) Antibody AP55723PU-N.The lane on the right is treated with the antigen-specific peptide.
CPA1933-100ul - PRKAR2B
Immunohistochemical analysis of PRKAR2B staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
CPA1933-100ul - PRKAR2B
Western blot analysis of PRKAR2B expression in HeLa (A); SHSY5Y (B); NIH3T3 (C) whole cell lysates.
TP309900 - PRKAR2B
TA313078 - PRKAR2B
Western blot analysis of extracts from HepG2 cells and K562 cells, using PKA-R2ß (Ab-113) antibody.The lane on the right is treated with the synthesized peptide.
TA313078 - PRKAR2B
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using PKA-R2ß (Ab-113) antibody.The picture on the right is treated with the synthesized peptide.

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PRKAR2B antibody
  Rabbit polyclonal PKA-R2beta (Ab-113) antibody  
Western blot analysis of extracts from HepG2 cells and K562 cells, using PKA-R2ß (Ab-113) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

PRKAR2B antibody
  Rabbit polyclonal PKA-R2beta (Ser113) antibody(Phospho-specific)  
PRKAR2B Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

PRKAR2B antibody
Immunohistochemistry (IHC) analyzes of PKA IIβ reg antibody (Cat.-No.: AP01453PU-N) in paraffin-embedded human cervix carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

PRKAR2B (N-term) antibody
Western blot analysis of anti-PRKAR2B Pab in mouse brain tissue lysate. PRKAR2B (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu, Ms WB
0.4 ml / €415.00
  OriGene Technologies GmbH

PRKAR2B (Center) antibody
Western blot analysis of PRKAR2B (arrow) using rabbit polyclonal PRKAR2B Antibody (Center) (Cat. #AP53444PU-N). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the PRKAR2B gene. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies GmbH

PRKAR2B pSer113 antibody
Western blot analysis of extracts from COS-7 cells treated with PMA using PKA-R2β (Phospho-Ser113) Antibody AP55723PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €300.00
  OriGene Technologies GmbH

PRKAR2B pSer113 antibody
Western blot analysis of extracts from COS-7 cells treated with PMA using PKA-R2β (Phospho-Ser113) Antibody AP55723PU-N.The lane on the right is treated with the antigen-specific peptide. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €230.00
  OriGene Technologies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PRKAR2B
  Recombinant protein of human protein kinase, cAMP-dependent, regulatory, type II, beta (PRKAR2B)  
PRKAR2B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Prkar2b (GFP-tagged) - Mouse protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL
Lenti ORF particles, Prkar2b (GFP-tagged) - Mouse protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Prkar2b (Myc-DDK-tagged) - Mouse protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL
Lenti ORF particles, Prkar2b (Myc-DDK-tagged) - Mouse protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Prkar2b (GFP-tagged ORF) - Rat protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL
Lenti ORF particles, Prkar2b (GFP-tagged ORF) - Rat protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Prkar2b (Myc-DDK-tagged ORF) - Rat protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL
Lenti ORF particles, Prkar2b (Myc-DDK-tagged ORF) - Rat protein kinase, cAMP dependent regulatory, type II beta (Prkar2b), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

12 Item(s)

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12 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. Mouse Lenti ORF Particle (2)
  2. Primary Antibody (7)
  3. Protein | Growth Factor (1)
  4. Rat Lenti ORF Particle (2)
Clonality
  1. Polyclonal (7)
Target
  1. PRKAR2B (8)
Property
  1. Center (1)
  2. N-term (1)
  3. pSer113 (2)
Reactivity
  1. Human (Hu) (7)
  2. Mouse (Ms) (6)
  3. Rat (Rt) (5)
Applications
  1. Western blot / Immunoblot (WB) (7)
  2. Enzyme Immunoassay (E) (2)
  3. Paraffin Sections (P) (2)
Presentation
  1. Aff - Purified (4)
  2. Purified (3)
Host
  1. Rabbit (7)
Images
  1. 1 image (7)
Images: Applications
  1. Western blot / Immunoblot (WB) (6)
  2. IHC (1)
  3. Paraffin Sections (P) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Manufacturer
  1. OriGene Technologies (12)
Service
  • OriGene Technologies GmbH
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  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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