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PTGER4 antibody

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Principal name

PTGER4 antibody

Alternative names for PTGER4 antibody

PTGER-4, PTGER2, PTGER-2, Prostaglandin E2 receptor EP4 subtype, PGE receptor, EP4 subtype, Prostanoid EP4 receptor

SwissProt ID

P32240 (Mouse), P35408 (Human), P43114 (Rat), Q28691 (Rabit), Q8MJ08 (Bovin)

Gene ID

5734 (PTGER4), 19219 (Ptger4)

Ncbi ID

NP_000949.1, 9606, NP_000949, NP_032991.1, NM_001136079, NM_000958

Available reactivities

Can (Canine), Eq (Equine), Hu (Human), Mky (Monkey), Ms (Mouse), Prim (Primate), Rt (Rat), Bear, Bt (Bat), Bov (Bovine), GP (Guinea Pig), Hst (Hamster), Op (Opossum), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection))

Background of PTGER4 antibody

Prostaglandin E2, a member of the autacoid family of lipid mediators, is a major renal cyclooxygenase product of arachidonic acid metabolism. Prostaglandin E2 binds to four G protein-coupled E-prostanoid receptors, designated EP1, EP2, EP3 and EP4. The expression and function of the prostaglandin E2 receptors have been highly characterized in kidney. EP1, which is predominantly expressed in the collecting duct, couples to Gq proteins to inhibit sodium absorption and increase in intracellular calcium, which act as second messengers. EP2 is coupled to Gs proteins, which stimulate adenylyl cyclase.EP2 has the lowest expression in kidney, but EP2 knockout mice exhibit saltsensitive hypertension, which suggests a role for EP2 in salt excretion. EP3, which is expressed in renal vessels, thick ascending limb and collecting duct, has at least six alternative splice variants that couple to Gi proteins to inhibit cAMP, which subsequently inhibit sodium and water transport. In uterus, EP3 induces the contraction of uterine smooth muscles. EP4 is expressed in glomerulus and collecting duct. It couples to Gs proteins, which stimulate adenylyl cyclase and regulate glomerular tone and renal renin release.

SP4549P - PTGER4
Cells expressing vector only - immunostained with target antibody
SP4549P - PTGER4
Cells expressing target protein - immunostained with target antibody
PAB6969 - PTGER4
PTGER4 polyclonal antibody ( Cat # PAB6969 ) ( 0.1 µg/ml ) staining of human testis lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence.
AP01202PU-N - PTGER4
Western blot (WB) analysis of EP4 antibody (Cat.-No.: AP01202PU-N) in extracts from COLO205 cells.
H00005734-D01P - PTGER4
Western Blot analysis of PTGER4 expression in transfected 293T cell line (H00005734-T04) by PTGER4 MaxPab polyclonal antibody.Lane 1: PTGER4 transfected lysate(53.10 KDa).Lane 2: Non-transfected lysate.
H00005734-D01P - PTGER4
PTGER4 MaxPab rabbit polyclonal antibody. Western Blot analysis of PTGER4 expression in Jurkat.
G099-1 - PTGER4
Immunofluorescence analysis of MCF7 cells, using PE2R4 Antibody. The picture on the right is treated with the synthesized peptide.
G099-1 - PTGER4
Western blot analysis of extracts from COLO205 cells, using PE2R4 Antibody. The lane on the right is treated with the synthesized peptide.
CPA1966-100ul - PTGER4
Western blot analysis of EP4 expression in Ramos (A); HeLa (B) whole cell lysates.
TP310932 - PTGER4
TA302476 - PTGER4
TA302476 (0.1µg/ml) staining of Human Testes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
TA317558 - PTGER4
Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA317558 - PTGER4
Anti-PTGER4 / EP4 antibody IHC of human Lung, Adenocarcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA317558 - PTGER4
Anti-PTGER4 / EP4 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA317558 - PTGER4
Anti-PTGER4 / EP4 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA317558 - PTGER4
Anti-PTGER4 / EP4 antibody IHC of human prostate, benign prostatic hyperplasia. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA317600 - PTGER4
Anti-PTGER4 / EP4 antibody IHC of human colon, ganglion. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA321244 - PTGER4
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: LoVo cells, Primary antibody: PTGER4 Antibody at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
TA325166 - PTGER4
PTGER4 Antibody (Center) (Cat. #TA325166) western blot analysis in HL-60,K562 cell line and mouse brain lysates (35ug/lane).This demonstrates the PTGER4 antibody detected the PTGER4 protein (arrow).

12 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

PTGER4 antibody
  Goat Polyclonal Antibody against EP4 prostaglandin receptor  
TA302476 (0.1µg/ml) staining of Human Testes lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu WB
0.1 mg / €360.00
  OriGene Technologies, Inc.

PTGER4 (C-term) antibody
  PTGER4 / EP4 Rabbit Polyclonal (C-Terminus) Antibody  
PTGER4 Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, GP, Hst, Hu, Mky, Ms, Op, Prim, Rb, Rt, Ze P
50 µg / €425.00
  OriGene Technologies, Inc.

PTGER4 (N-Term, Extracell. Dom.) antibody
  PTGER4 / EP4 Rabbit Polyclonal (N-Terminus) Antibody  
PTGER4 Rabbit Aff - Purified Hu, Mky, Prim ICC/IF, P
50 µg / €425.00
  OriGene Technologies, Inc.

PTGER4 antibody
  Anti-PTGER4 Rabbit Polyclonal Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane: LoVo cells, Primary antibody: PTGER4 Antibody at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

PTGER4 antibody
  Rabbit polyclonal PTGER4 Antibody (Center)  
PTGER4 Antibody (Center) (Cat. #TA325166) western blot analysis in HL-60,K562 cell line and mouse brain lysates (35ug/lane).This demonstrates the PTGER4 antibody detected the PTGER4 protein (arrow). Rabbit IgG Purified Bov, Hu, Ms, Rb, Rt WB
0.4 ml / €415.00
  OriGene Technologies, Inc.

PTGER4 antibody
Western blot (WB) analysis of EP4 antibody (Cat.-No.: AP01202PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu ICC/IF, WB
0.1 mg / €370.00
  OriGene Technologies GmbH

PTGER4 (C-term) antibody
Cells expressing vector only - immunostained with target antibody Rabbit Aff - Purified Hu, Mky ICC/IF, P
50 µg / €425.00
  OriGene Technologies GmbH
+1 additional image

CRISPR

Catalog No. Species Donor Vector  

PTGER4 - human gene knockout kit via CRISPR
PTGER4 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTGER4 - human gene knockout kit via CRISPR
PTGER4 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTGER4 - human gene knockout kit via CRISPR
PTGER4 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

PTGER4 - human gene knockout kit via CRISPR
PTGER4 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

PTGER4
  Recombinant protein of human prostaglandin E receptor 4 (subtype EP4) (PTGER4)  
PTGER4 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.		 HEK293 cells
20 µg / €748.00
  OriGene Technologies, Inc.

12 Item(s)

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12 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. CRISPR (4)
  2. Primary Antibody (7)
  3. Protein | Growth Factor (1)
Clonality
  1. Polyclonal (7)
Target
  1. PTGER4 (8)
Property
  1. C-term (2)
  2. N-Term, Extracell. Dom. (1)
Reactivity
  1. Human (Hu) (7)
  2. Monkey (Mky) (3)
  3. Mouse (Ms) (3)
  4. Rat (Rt) (3)
  5. Bovine (Bov) (2)
  6. Canine (Can) (2)
  7. Primate (Prim) (2)
  8. Rabbit (Rb) (2)
  9. Bear (1)
  10. Bat (Bt) (1)
  11. Elephant (1)
  12. Equine (Eq) (1)
  13. Guinea Pig (GP) (1)
  14. Hamster (Hst) (1)
  15. Opossum (Op) (1)
  16. Zebrafish (Ze) (1)
Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (3)
  3. Paraffin Sections (P) (3)
  4. Enzyme Immunoassay (E) (1)
Presentation
  1. Aff - Purified (5)
  2. Purified (2)
Host
  1. Rabbit (6)
  2. Goat (1)
Images
  1. 1 image (6)
Images: Applications
  1. Western blot / Immunoblot (WB) (4)
  2. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Species (Protein)
  1. Human (1)
Source
  1. HEK293 cells (1)
Species (CRISPR)
  1. Human (4)
Donor Vector
  1. GFP-Puro (1)
  2. Luciferase-Puro (1)
  3. RFP-BSD (1)
  4. mBFP-Neo (1)
Manufacturer
  1. OriGene Technologies (12)
Service
  • OriGene Technologies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info-de@origene.com
  • orders: ordering-de@origene.com
 
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