PTPN12 antibody
Principal name
PTPN12 antibody
Alternative names for PTPN12 antibody
PTP-PEST, PTPG1, Protein-tyrosine phosphatase G1, Tyrosine-protein phosphatase non-receptor type 12
Gene ID
5782 (PTPN12)
Ncbi ID
NP_001124480.1, 9606, NP_002826, NP_001124480, NM_002835, NM_001131008
Available reactivities
Available hosts
Available applications
Immunoprecipitation (IP), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E), Paraffin Sections (P)
Background of PTPN12 antibody
The protein encoded byThis gene is a member ofThe protein tyrosine phosphatase (PTP) family. PTPs are sigling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.This PTP contains a C-termil PEST motif, which serves as a protein-protein interaction domain, and may regulate protein intracellular half-life.This PTP was found to bind and dephosphorylateThe product ofThe oncogene c-ABL and thus may play a role in oncogenesis.This PTP was also shown to interact with, and dephosphorylate, various products related to cytoskeletal structure and cell adhesion, such as p130 (Cas), CAKbeta/PTK2B, PSTPIP1, and paxillin.This suggests it has a regulatory role in controlling cell shape and mobility. Altertive splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA351564 | PTPN12 antibody |
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| Rabbit Polyclonal Anti-PTPN12 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
 +2 additional images |
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| AM05260PU-N | PTPN12 antibody |
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 |
Mouse | IgG1 | AG25 | Purified | Bov, Hu, Ms, Rt | IP, WB |
0.1 mg /
€400.00
|
| OriGene Technologies GmbH | |||||||
| AM31947PU-N | PTPN12 antibody |
||||||
 |
Mouse | IgG2a | 4G6 | Purified | Hu | E, P, WB |
50 µg /
€475.00
|
| OriGene Technologies GmbH | |||||||
| +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP307952 | PTPN12 (transcript variant 1) |
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| Recombinant protein of human protein tyrosine phosphatase, non-receptor type 12 (PTPN12), transcript variant 1 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY419063 | PTPN12 overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |