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RBPJL antibody

Principal name

RBPJL antibody

Alternative names for RBPJL antibody

RBPL, RBPSUHL, Transcription factor RBP-L, Recombining binding protein suppressor of hairless-like protein

SwissProt ID

O08674 (Mouse), Q9UBG7 (Human)

Gene ID

11317 (RBPJL), 19668 (Rbpjl)

Ncbi ID

9606, NP_055091, NM_014276, NP_055091.2, NP_033062.1, NM_009036

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Dros (Drosophila), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of RBPJL antibody

RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein. In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). RBPJL is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.In mouse, recombining binding protein L (RBP-L) is a transcription factor that binds to DNA sequences almost identical to that bound by the Notch receptor signalling pathway transcription factor RBP-J. However, unlike RBP-J, RBP-L does not interact with Notch receptors. RBP-L has been shown to activate transcription in concert with Epstein-Barr virus nuclear antigen-2 (EBNA2). The protein encoded by this gene is similar in sequence to the mouse RPB-L protein and Drosophila suppressor of hairless protein.

General readings

Beres, T.M., et al. Mol. Cell. Biol. 26(1):117-130(2006)
Deloukas, P., et al. Nature 414(6866):865-871(2001)
Nakagawa, H., et al. Oncogene 19(2):210-216(2000)
Tani, S., et al. J. Hum. Genet. 44(1):73-75(1999)
Minoguchi, S., et al. Mol. Cell. Biol. 17(5):2679-2687(1997)

Western Blot analysis of RBPJL expression in transfected 293T cell line (H00011317-T01) by RBPJL MaxPab polyclonal antibody.Lane 1: RBPSUHL transfected lysate(56.87 KDa).Lane 2: Non-transfected lysate.

H00011317-B01

Human Jurkat; WB Suggested Anti-RBPJL Antibody Titration: 2.5ug/ml. Positive Control: Jurkat cell lysate; RBPJL antibody - N-terminal region (ARP34313_T100) in Human Jurkat cells using Western Blot

ARP34313_T100

Western Blot analysis of RBPJL expression in transfected 293T cell line (H00011317-T02) by RBPJL MaxPab polyclonal antibody.Lane 1: RBPJL transfected lysate(56.80 KDa).Lane 2: Non-transfected lysate.

H00011317-D01P

Human 721_B; WB Suggested Anti-RBPJL Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: 721_B cell lysate. RBPJL is supported by BioGPS gene expression data to be expressed in 721_B.; RBPJL antibody - middle region (ARP34710_P050) in Human 721_B cells using Western Blot

ARP34710_P050

RBPJL Antibody (N-term) (Cat. #TA324465) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the RBPJL antibody detected the RBPJL protein (arrow).

TA324465

RBPJL Antibody (N-term) (Cat. #TA324465)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RBPJL Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

TA324465

RBPJL Antibody (N-term) (Cat. #TA324465) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.

TA324465

WB Suggested Anti-RBPJL Antibody Titration: 2.5 ug/ml; Positive Control: Jurkat cell lysate

TA335630

WB Suggested Anti-RBPJL Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: 721_B cell lysateRBPJL is supported by BioGPS gene expression data to be expressed in 721_B

TA337302

Host: Rabbit; Target Name: RBPJL; Sample Tissue: Lymph Tumor lysates; Antibody Dilution: 1.0 ug/ml

TA343727

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA324465	RBPJL (N-term) antibody
	Rabbit polyclonal RBPJL Antibody (N-term)
	Rabbit	Ig	Aff - Purified	Hu	P, WB	0.4 ml / €415.00
						OriGene Technologies, Inc.
+2 additional images

Lysates

Catalog No.
LY415401	RBPJL overexpression lysate
		0.1 mg / €495.00
		OriGene Technologies, Inc.

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