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ROS1 antibody

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Principal name

ROS1 antibody

Alternative names for ROS1 antibody

ROS, c-Ros-1, Tyrosine-protein kinase ROS, Proto-oncogene tyrosine-protein kinase ROS

SwissProt ID

P08922 (Human), P08941 (Chick), Q63132 (Rat), Q78DX7 (Mouse)

Gene ID

6098 (ROS1)

Ncbi ID

9606, NP_002935.2, NM_002944

Available reactivities

Hu (Human), Bov (Bovine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F), Immunoprecipitation (IP)

Background of ROS1 antibody

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The tyrosine kinase (TK) group is mainly involved in the regulation of cell-cell interactions such as differentiation, adhesion, motility and death. There are currently about 90 TK genes sequenced, 58 are of receptor protein TK (e.g. EGFR, EPH, FGFR, PDGFR, TRK, and VEGFR families), and 32 of cytosolic TK (e.g. ABL, FAK, JAK, and SRC families).

PAB3387 - ROS1
Formalin-fixed and paraffin-embedded human cancer tissue reacted with ROS1 polyclonal antibody ( Cat # PAB3387 ) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry ; clinical relevance has not been evaluated. HC = hepatocarcinoma.
PAB3387 - ROS1
Western blot analysis of ROS1 polyclonal antibody ( Cat # PAB3387 ) in HL-60 cell lysate. ROS ( arrow ) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
CPA3006-100ul - ROS1
Western blot analysis of ROS (pY2114) expression in SKOVCAR (A); Raw264.7 (B); PC12 (C) whole cell lysates.
TA805678 - ROS1
Immunohistochemical staining of paraffin-embedded Carcinoma of ROS1 positive Human lung tissue using anti-ROS1 mouse monoclonal antibody. (TA805678; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
TA805678 - ROS1
Immunohistochemical staining of paraffin-embedded Carcinoma of ROS1 positive Human lung tissue using anti-ROS1 mouse monoclonal antibody. (TA805678; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
TA805678 - ROS1
Immunohistochemical staining of paraffin-embedded Carcinoma of ROS1 positive Human lung tissue using anti-ROS1 mouse monoclonal antibody. (TA805678; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)
TA805678 - ROS1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS1 (RC220652, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROS1.
TA805734 - ROS1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS1 (RC220652, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROS1.
TA805804 - ROS1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS1 (RC220652, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROS1.
TA805825 - ROS1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS1 (RC220652, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROS1.
TA322925 - ROS1
Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using ROS1 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA324969 - ROS1
Western blot analysis of anti-ROS Pab (Cat. #TA324969) in HL-60 cell lysate. ROS (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
TA324969 - ROS1
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

ROS1 antibody
  ROS1 mouse monoclonal antibody, clone OTI1F3 (formerly 1F3)  
Immunohistochemical staining of paraffin-embedded Carcinoma of ROS1 positive Human lung tissue using anti-ROS1 mouse monoclonal antibody. (TA805678; heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) Mouse IgG1 OTI1F3 Purified Hu P, WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
+3 additional images

Highly validated antibody!

TrueMAB

ROS1 antibody
  Anti-ROS1 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using ROS1 antibody at dilution 1/40, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

ROS1 (N-term) antibody
  Rabbit polyclonal ROS Antibody (N-term)  
Western blot analysis of anti-ROS Pab (Cat. #TA324969) in HL-60 cell lysate. ROS (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence. Rabbit Ig Purified Hu ICC/IF, P, WB
0.4 ml / €415.00
  OriGene Technologies, Inc.
+1 additional image

ROS1 antibody
  ROS1 mouse monoclonal antibody, clone OTI5D2 (formerly 5D2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS1 (RC220652, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROS1. Mouse IgG1 OTI5D2 Purified Hu WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
 

TrueMAB

ROS1 antibody
  ROS1 mouse monoclonal antibody, clone OTI1A1 (formerly 1A1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS1 (RC220652, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROS1. Mouse IgG2a OTI1A1 Purified Hu ICC/IF, P, WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
 

TrueMAB

ROS1 antibody
  ROS1 mouse monoclonal antibody, clone OTI7E4 (formerly 7E4)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ROS1 (RC220652, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ROS1. Mouse IgG1 OTI7E4 Purified Hu WB
0.1 ml / €360.00
  OriGene Technologies, Inc.
 

TrueMAB

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, ROS1 (Myc-DDK tagged) - Human c-ros oncogene 1, receptor tyrosine kinase (ROS1), 200 uL, >10^7 TU/mL
Lenti ORF particles, ROS1 (Myc-DDK tagged) - Human c-ros oncogene 1, receptor tyrosine kinase (ROS1), 200 uL, >10^7 TU/mL  
200 µl / €2,420.00
  OriGene Technologies, Inc.
 

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Available Filters

Product Type
  1. Human Lenti ORF Particle (1)
  2. Primary Antibody (6)
Clonality
  1. Monoclonal (4)
  2. Polyclonal (2)
Target
  1. ROS1 (6)
Property
  1. N-term (1)
Reactivity
  1. Human (Hu) (6)
  2. Mouse (Ms) (1)
  3. Rat (Rt) (1)
Applications
  1. Western blot / Immunoblot (WB) (5)
  2. Paraffin Sections (P) (4)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (2)
  4. Enzyme Immunoassay (E) (1)
Presentation
  1. Purified (6)
Host
  1. Mouse (4)
  2. Rabbit (2)
Images
  1. 1 image (6)
  2. 3+ images (1)
Images: Applications
  1. Western blot / Immunoblot (WB) (5)
  2. IHC (2)
  3. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (7)
Service
  • OriGene Technologies GmbH
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  • D-32052 Herford
  • Germany
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  • fax: +49-5221-34606-11
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