SAR1B antibody
Principal name
SAR1B antibody
Alternative names for SAR1B antibody
SAR1B, SARA2, SARB, GTP-binding protein SAR1b, GTBPB
Ncbi ID
9606, NP_001028675, NP_001028675.1, NP_057187.1, NM_016103, NM_001033503, NP_057187, NP_079811.1, NM_025535, NM_001009622
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)
Background of SAR1B antibody
SAR1B belongs to the small GTPase superfamily, SAR1 family. It is involved in transport from the endoplasmic reticulum to the Golgi apparatus and is activated by the guanine nucleotide exchange factor PREB. SAR1B is involved in the selection of the protein cargo and the assembly of the COPII coat complex. Defects in SAR1B are the cause of chylomicron retention disease (CMRD). CMRD is an autosomal recessive disorder of severe fat malabsorption associated with failure to thrive in infancy. The conditions are characterized by deficiency of fat-soluble vitamins, low blood cholesterol levels, and a selective absence of chylomicrons from blood. Affected individuals accumulate chylomicron-like particles in membrane-bound compartments of enterocytes, which contain large cytosolic lipid droplets.
Cellular localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.
General readings
Evans K, Burdge GC, Wootton SA, Collins JM, Clark ML, Tan GD, Karpe F, Frayn KN.
Tissue-specific stable isotope measurements of postprandial lipid metabolism in familial combined hyperlipidaemia.
Atherosclerosis. 2007 Apr 25; [Epub ahead of print]
PMID: 17466309
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA302583 | SAR1B antibody |
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| Goat Polyclonal Antibody against SAR1B / SARA2 | |||||||
 |
Goat | Aff - Purified | Hu, Ms, Rt | WB |
0.1 mg /
€360.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA312375 | SAR1B antibody |
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| Rabbit polyclonal anti-SAR1B antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
 +1 additional image |
|||||||
| AP53796PU-N | SAR1B (Center) antibody |
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 |
Rabbit | Ig | Aff - Purified | Hu | P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
| +1 additional image |
|||||||
Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP310593 | SAR1B (transcript variant 2) |
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| Recombinant protein of human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 2 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
| TP313692 | SAR1B (transcript variant 1) |
||||
| Recombinant protein of human SAR1 homolog B (S. cerevisiae) (SAR1B), transcript variant 1 | |||||
 |
Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY402500 | SAR1B overexpression lysate |
|
 |
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. | ||
| LY422370 | SAR1B overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Mouse Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| MR201981L2V | Lenti ORF particles, Sar1b (GFP-tagged) - Mouse SAR1 gene homolog B (S. cerevisiae) (Sar1b), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| MR201981L1V | Lenti ORF particles, Sar1b (Myc-DDK-tagged) - Mouse SAR1 gene homolog B (S. cerevisiae) (Sar1b), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR205370L2V | Lenti ORF particles, Sar1b (GFP-tagged ORF) - Rat SAR1 homolog B (S. cerevisiae) (Sar1b), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€930.00
|
|
| OriGene Technologies, Inc. | ||
| RR205370L1V | Lenti ORF particles, Sar1b (Myc-DDK-tagged ORF) - Rat SAR1 homolog B (S. cerevisiae) (Sar1b), 200 uL, >10^7 TU/mL |
|
|
200 µl /
€830.00
|
|
| OriGene Technologies, Inc. | ||