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SCN5A antibody

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Principal name

SCN5A antibody

Alternative names for SCN5A antibody

HB1, HB2, HH1, HBBD, CDCD2, Nav1.5, LQT3, Sodium channel protein type 5 subunit alpha, Sodium channel protein type V subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.5, Sodium channel protein cardiac muscle subunit alpha

SwissProt ID

P15389 (Rat), Q14524 (Human)

Gene ID

6331 (SCN5A), 25665 (Scn5a)

Ncbi ID

NP_000326.2, 9606, NP_932173, NP_000326, NP_001153634.1, NM_000335

Available reactivities

Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Fi (Fish), Hst (Hamster), Hu (Human), Mky (Monkey), Ms (Mouse), Op (Opossum), Por (Porcine), Prim (Primate), Rt (Rat), Tr (Turkey), Bear, Rb (Rabbit), Ze (Zebrafish), GP (Guinea Pig)

Available hosts

Goat, Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of SCN5A antibody

Voltage-gated sodium channesl (VGSCs) mediate regenerative cell membrane depolarization and conduction of electrical signalling in nerves and muscles. They have also been detected in lymphocytes, glia, and fibroblasts. VGSC proteins are comprised of a core alpha-subunit, together with one or more additional regulatoy beta-subunit. VCSC expression has been detected in a number of tumour cell lines and has been implicated in the metastatic behaviour of breast and prostate cancer cells. Na(v)1.5, the major cardiac voltage-gated Na(+) channel, plays a central role in the generation of the cardiac action potential and in the propagation of electrical impulses in the heart. Its importance for normal heart function has been recently exemplified by reports of numerous mutations found in the gene SCN5A which encodes Na(v)1.5.

General readings

Shah,V.N., (2006) Proc. Natl. Acad. Sci. U.S.A. 103 (10), 3592-3597

AP07905PU-N - SCN5A
Figure 1. Staining SCN5A in Brain, Cortex by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue.
ARP35542_P050 - SCN5A
MCF7 Whole Cell; Host: Rabbit. Target Name:SCN5A. Sample Tissue:MCF7 Whole Cell. Lane A: Primary Antibody . Lane B:Primary Antibody + Blocking Peptide . Primary Antibody Concentration:1ug/ml. Peptide Concentration: 5ug/ml. Lysate Quantity: 25ug/lane/Lane. Gel Concentration: 0.12.; SCN5A antibody - C-terminal region (ARP35542_P050) in MCF7 Whole Cell cells using Western Blot
ARP35542_P050 - SCN5A
Human SW620; WB Suggested Anti-SCN5A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:312500. Positive Control: SW620 cell lysate. SCN5A is supported by BioGPS gene expression data to be expressed in SW620.; SCN5A antibody - C-terminal region (ARP35542_P050) in Human SW620 cells using Western Blot
ARP34934_P050 - SCN5A
Hum. Fetal Muscle; Host: Rabbit. Target Name: SCN5A. Sample Tissue: Human Fetal Muscle. Antibody Dilution: 1.0ug/ml.; SCN5A antibody - N-terminal region (ARP34934_P050) in Hum. Fetal Muscle cells using Western Blot
ARP34934_P050 - SCN5A
Human Muscle; WB Suggested Anti-SCN5A Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Human Muscle; SCN5A antibody - N-terminal region (ARP34934_P050) in Human Muscle cells using Western Blot
TA314511 - SCN5A
Western blot analysis of extracts from HuvEc cells, using Sodium Channel-pan Antibody (#TA314511).The lane on the right is treated with the synthesized peptide.
TA314511 - SCN5A
Immunohistochemical analysis of paraffin-embedded human heart tissue using Sodium Channel-pan antibody (#TA314511).The picture on the right is treated with the synthesized peptide.
TA321976 - SCN5A
Predicted cell location: Cytoplasm. Positive control: Human breast and ovarian cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using SCN5A antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200)
TA321976 - SCN5A
Predicted cell location: Cytoplasm. Positive control: Human breast and ovarian cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using SCN5A antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA321977 - SCN5A
Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using SCN5A antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200)
TA328703 - SCN5A
Western blot analysis of Nav1.5 in human-Nav1.5 transfected HEK-293 cells: 1. Anti-Human-Nav1.5 antibody, (1:200). 2. Anti-Human-Nav1.5 antibody, preincubated with the control peptide antigen
TA328703 - SCN5A
Expression of Nav1.5 in rat cardiac muscle. Immunohistochemical staining of Nav1.5 in rat myocardium paraffin-embedded section using Anti-Human Nav1.5 antibody, (1:100). Staining is specific for cardiomyocytes while smooth muscles cells in the artery walls are negative (red arrows). Hematoxilin is used as the counterstain.
TA329031 - SCN5A
Western blot analysis of rat heart membranes: 1. Anti-Nav1.5 antibody , (1:200). 2. Anti-Nav1.5 antibody, preincubated with the control peptide antigen.
TA329031 - SCN5A
Western blot analysis of Nav1.5 in human-Nav1.5 transfected HEK-293 cells: 1. Anti-Nav1.5 antibody , (1:200). 2. Anti-Nav1.5 antibody, preincubated with the control peptide antigen.
TA329031 - SCN5A
Expression of Nav1.5 in rat heart. Immunohistochemical staining of Nav1.5 in rat myocardium paraffin-embedded sections using Anti-Nav1.5 antibody , (1:100). Staining is specific for cardiomyocytes while smooth muscles cells in the small vessels are negative (red arrows). Hematoxilin is used as the counterstain.
TA338380 - SCN5A
WB Suggested Anti-SCN5A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: Human Muscle
TA338380 - SCN5A
Host: Rabbit; Target Name: SCN5A; Sample Tissue: Human Fetal Muscle; Antibody Dilution: 1.0 ug/ml
TA338381 - SCN5A
WB Suggested Anti-SCN5A Antibody Titration: HEK cel lysate; HEK cel with HuNav1.5 transfected lysate; Mouse Heart lysate 80 ug protein on gelQC Antibodies 1:100 in PBS/Tweensecondary antibodie 1:10.000 ( IRDYE 800 CWGoat anti Rabbit IgG) analyse with the
TA338791 - SCN5A
WB Suggested Anti-SCN5A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: SW620 cell lysate SCN5A is supported by BioGPS gene expression data to be expressed in SW620
TA338791 - SCN5A
Host: Rabbit; Target Name:SCN5A; Sample Tissue:MCF7 Whole Cell; Lane A: Primary Antibody; Lane B:Primary Antibody + Blocking Peptide ; Primary Antibody Concentration:1 ug/ml; Peptide Concentration: 5ug/ml; Lysate Quantity: 25ug/lane/Lane; Gel Concentratio
TA341178 - SCN5A
Anti-SCN5A / Nav1.5 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
TA353459 - SCN5A
Two colour Immunocytochemistry on Nav1.5 overexpressing 293 cells (150uL per slide): A. Anti-nNav 1.5 [4G8:1G7], B. DAPI

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SCN5A antibody
  Rabbit polyclonal Sodium Channel-pan antibody  
Western blot analysis of extracts from HuvEc cells, using Sodium Channel-pan Antibody (#TA314511).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

SCN5A antibody
  Anti-SCN5A Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human breast and ovarian cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human breast cancer tissue using SCN5A antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.
+1 additional image

SCN5A antibody
  Anti-SCN5A Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using SCN5A antibody at dilution 1/25, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €335.00
  OriGene Technologies, Inc.

SCN5A antibody
  Rabbit Polyclonal Anti-Human NaV1.5  
Western blot analysis of Nav1.5 in human-Nav1.5 transfected HEK-293 cells: 1. Anti-Human-Nav1.5 antibody, (1:200). 2. Anti-Human-Nav1.5 antibody, preincubated with the control peptide antigen Rabbit Purified Hu, Rt WB
0.2 ml / €585.00
  OriGene Technologies, Inc.
+1 additional image

SCN5A antibody
  Rabbit polyclonal Anti-NaV1.5  
Western blot analysis of rat heart membranes: 1. Anti-Nav1.5 antibody , (1:200). 2. Anti-Nav1.5 antibody, preincubated with the control peptide antigen. Rabbit Purified Hu, Ms, Rt WB
0.2 ml / €585.00
  OriGene Technologies, Inc.
+2 additional images

SCN5A (1548-1558) antibody
Figure 1. Staining SCN5A in Brain, Cortex by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Goat Aff - Purified Elephant, Hu, Slime Mold E, P
50 µg / €425.00
  OriGene Technologies GmbH

SCN5A antibody
SCN5A Rabbit Purified Hu C, E, WB
0.1 mg / €450.00
  OriGene Technologies GmbH

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, SCN5A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 2, 200 uL, >10^7 TU/mL
Lenti ORF particles, SCN5A (Myc-DDK tagged) - Human sodium channel, voltage-gated, type V, alpha subunit (SCN5A), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €2,420.00
  OriGene Technologies, Inc.
 

8 Item(s)

per page

Available Filters

Product Type
  1. Human Lenti ORF Particle (1)
  2. Primary Antibody (7)
Clonality
  1. Polyclonal (7)
Target
  1. SCN5A (7)
Property
  1. 1548-1558 (1)
Reactivity
  1. Human (Hu) (7)
  2. Rat (Rt) (5)
  3. Mouse (Ms) (4)
  4. Elephant (1)
  5. Slime Mold (1)
Applications
  1. Enzyme Immunoassay (E) (5)
  2. Paraffin Sections (P) (4)
  3. Western blot / Immunoblot (WB) (4)
  4. Frozen sections (C) (1)
Presentation
  1. Purified (6)
  2. Aff - Purified (1)
Host
  1. Rabbit (6)
  2. Goat (1)
Images
  1. 1 image (6)
  2. 3+ images (1)
Images: Applications
  1. IHC (5)
  2. Western blot / Immunoblot (WB) (3)
  3. Paraffin Sections (P) (1)
Manufacturer
  1. OriGene Technologies (8)
Service
  • OriGene Technologies GmbH
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  • Germany
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  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
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  • orders: ordering-de@origene.com
 
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