SFTPC antibody
Principal name
SFTPC antibody
Alternative names for SFTPC antibody
Surfactant protein C, SP-C, SFTP2, SP5, Pulmonary surfactant-associated protein C, Pulmonary surfactant-associated proteolipid SPL(Val)
SwissProt ID
P0AFN2 (Ecoli), P11685 (Rat), P11686 (Human), P15783 (Bovin), P15785 (Pig), P21841 (Mouse), P22397 (Canfa), P22398 (Rabit)
Ncbi ID
9606, NP_003009, NP_001165828, NP_001165828.1, 10090, NM_003018, NM_017342, NM_001172410
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)
Background of SFTPC antibody
There are four surfactant-specific proteins, designated surfactant protein A (SP-A), SP-B, SP-C and SP-D respectively. SP-A and SP-D are hydrophilic surfactant proteins and are members of the collectin family. SP-B and SP-C are hydrophobic surfactant proteins and may be the most appropriate indicators for the evolutionary origin of surfactant.
SP-C is a 34-35 amino acid peptide, of 4 kD that is proteolytically processed from a 21 kD precursor protein. SP-C is initiated early in the embryogenic period of lung formation, where SP-C transcripts are detected uniformly in epithelial cells lining the primitive airways. During lung development SP-C expression is decreased in cells of the proximal conducting portion of the lung. Ultimately SP-C is expressed selectively in type II epithelial cells in the alveolus of the lung. SP-C is secreted into the airspace where it enhances the spreading and stability of surfactant phospholipids in the alveolus. SP-C plays an important role in the spreading and stabilization of phospholipid films in the alveolus. SP-C is essential for air-breathing in mammals and is therefore largely conserved. Deficiency of SP-C and other surfactant components is associated with respiratory distress syndrome (RDS) in premature infants and adults with respiratory distress syndrome (ARDS).
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA332441 | SFTPC antibody |
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| Rabbit anti-SFTPC Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
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| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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| AP26404PU-N | SFTPC (1-33) antibody |
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 |
Rabbit | IgG | Purified | Hu, Ms | C, P, WB |
0.1 mg /
€410.00
|
|
| OriGene Technologies GmbH | |||||||
| AP53886PU-N | SFTPC (N-term) antibody |
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 |
Rabbit | Ig | Aff - Purified | Bov, Hu, Ms | F, ICC/IF, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
| +1 additional image |
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