Shigella antibody
Principal name
Shigella antibody
Available reactivities
Available hosts
Available applications
Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Agglutination (AGG), Dot blot (Dot), ELISA (capture) (E(capture)), ELISA (detection) (E(detection))
Background of Shigella antibody
Shigella are Gram-negative, non-motile, non-sporeforming rod-shaped bacteria. Infection with Shigella causes severe gastric symptoms including abdominal pain, cramps, diarrhoea, fever, vomiting and blood, pus or mucus in stools. Shigella rarely occurs in animals being principally a disease of humans and other primates such as monkeys and chimpanzees. The organism is frequently found in water polluted with human faeces. The disease is caused when virulent Shigella organisms attach to, and penetrate, epithelial cells of the intestinal mucosa. After invasion, they multiply intracellularly, and spread to contiguous epithelial cells resulting in tissue destruction. Some strains produce enterotoxin and Shiga toxin (very much like the verotoxin of E. coli O157:H7).
General readings
1. Sapsford, K.E., et al., (2004), Detection of campylobacter and shigella species in food samples using an
array biosensor”, Analytical Chemistry, 76(2): 433-440.