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SIX3 antibody

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Principal name

SIX3 antibody

Alternative names for SIX3 antibody

Homeobox protein SIX3, Sine oculis homeobox homolog 3

SwissProt ID

O42406 (Chick), O95343 (Human), Q62233 (Mouse)

Gene ID

6496 (SIX3), 20473 (Six3)

Ncbi ID

9606, NP_005404, NM_011381, NP_005404.1, NM_005413

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Chk (Chicken), Ze (Zebrafish), GP (Guinea Pig)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection))

Background of SIX3 antibody

The SIX proteins (sine oculis) are a family of homeodomain transcription factors that share a conserved DNA binding domain. Two of these family members Six3 and Six6 (also designated Optx2 and Six9) are required for the specification and proliferation of the eye field in vertebrates, and, therefore, are the vertebrate homologues most closely related to the Drosophila sine oculis protein, which has an essential role in controlling compound eye development. Six3 and Six6 expression largely overlap during development of specific tissues, such as retina, hypothalamus, and pituitary. The human Six6 gene maps to chromosome 14q22.3-q23. Haploinsufficiency of Six6 may cause several developmental disorders, including bilateral anophthalmia and pituitary anomalies. The gene encoding the human Six3 protein maps to chromosome 2p21-p22, a region associated with holoprosencephaly type 2 (HPE2). Deletion of Six3 may be associated with HPE2 disorder, a common, severe malformation of the brain that results from incomplete cleavage of the forebrain during early embryogenesis.

General readings

Appolloni,I., (2008) Cereb. Cortex 18 (3), 553-562

H00006496-M01 - SIX3
SIX3 monoclonal antibody (M01), clone 3D12. Western Blot analysis of SIX3 expression in human thyroid(diffuse hyperplasia).
H00006496-M01 - SIX3
SIX3 monoclonal antibody (M01), clone 3D12. Western Blot analysis of SIX3 expression in MES-SA/Dx5 ( Cat # L021V1 ).
H00006496-M01 - SIX3
SIX3 monoclonal antibody (M01), clone 3D12 Western Blot analysis of SIX3 expression in 293 ( Cat # L026V1 ).
H00006496-M02 - SIX3
SIX3 monoclonal antibody (M02), clone 3F1. Western Blot analysis of SIX3 expression in human thyroid(diffuse hyperplasia).
H00006496-M02 - SIX3
SIX3 monoclonal antibody (M02), clone 3F1. Western Blot analysis of SIX3 expression in FHs 173 WE.
H00006496-M02 - SIX3
SIX3 monoclonal antibody (M02), clone 3F1. Western Blot analysis of SIX3 expression in MES-SA/Dx5 ( Cat # L021V1 ).
H00006496-M02 - SIX3
SIX3 monoclonal antibody (M02), clone 3F1 Western Blot analysis of SIX3 expression in 293 ( Cat # L026V1 ).
H00006496-M04 - SIX3
SIX3 monoclonal antibody (M04), clone 1A2 Western Blot analysis of SIX3 expression in 293 ( Cat # L026V1 ).
H00006496-M04 - SIX3
SIX3 monoclonal antibody (M04), clone 1A2. Western Blot analysis of SIX3 expression in human thyroid(diffuse hyperplasia).
H00006496-M04 - SIX3
SIX3 monoclonal antibody (M04), clone 1A2. Western Blot analysis of SIX3 expression in FHs 173 WE.
H00006496-M04 - SIX3
SIX3 monoclonal antibody (M04), clone 1A2. Western Blot analysis of SIX3 expression in MES-SA/Dx5 ( Cat # L021V1 ).
H00006496-M08 - SIX3
SIX3 monoclonal antibody (M08), clone 2B9. Western Blot analysis of SIX3 expression in human thyroid(diffuse hyperplasia).
H00006496-M08 - SIX3
SIX3 monoclonal antibody (M08), clone 2B9. Western Blot analysis of SIX3 expression in FHs 173 WE.
H00006496-M08 - SIX3
SIX3 monoclonal antibody (M08), clone 2B9. Western Blot analysis of SIX3 expression in MES-SA/Dx5 ( Cat # L021V1 ).
H00006496-M08 - SIX3
SIX3 monoclonal antibody (M08), clone 2B9 Western Blot analysis of SIX3 expression in 293 ( Cat # L026V1 ).
H00006496-M10 - SIX3
SIX3 monoclonal antibody (M10), clone 4H6. Western Blot analysis of SIX3 expression in human thyroid(diffuse hyperplasia).
H00006496-M10 - SIX3
SIX3 monoclonal antibody (M10), clone 4H6. Western Blot analysis of SIX3 expression in FHs 173 WE.
H00006496-M10 - SIX3
SIX3 monoclonal antibody (M10), clone 4H6. Western Blot analysis of SIX3 expression in MES-SA/Dx5 ( Cat # L021V1 ).
H00006496-M10 - SIX3
SIX3 monoclonal antibody (M10), clone 4H6 Western Blot analysis of SIX3 expression in 293 ( Cat # L026V1 ).
AP06651PU-N - SIX3/6
Western blot (WB) analysis of Six3/6 antibody Cat.-No AP06651PU-N in extracts from HUVEC cells.
AP06651PU-N - SIX3/6
Western blot (WB) analysis of Six3/6 antibody Cat.-No AP06651PU-N at 1/500 dilution. 
Lane 1: HEK293T whole cell lysate.
Lane 2: Raw264.7 whole cell lysate.
Lane 3: H9C2 whole cell lysate.
ARP32369_P050 - SIX3
Human HepG2; WB Suggested Anti-SIX3 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; SIX3 antibody - N-terminal region (ARP32369_P050) in Human HepG2 cells using Western Blot
ARP37135_P050 - SIX3
Mouse Thymus; WB Suggested Anti-Six3 Antibody Titration: 0.2-1 ug/ml. Positive Control: Mouse Thymus; Six3 antibody - C-terminal region (ARP37135_P050) in Mouse Thymus cells using Western Blot
CPA2068-100ul - SIX3
Western blot analysis of SIX3 expression in HeLa (A); Jurkat (B); Raw264.7 (C); PC12 (D) whole cell lysates.
TA314537 - SIX3
Western blot analysis of extracts from A549 cells, using SIX3 antibody.The lane on the right is treated with the synthesized peptide.
TA324591 - SIX3
SIX3 Antibody (Center) (Cat. #TA324591) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the SIX3 antibody detected the SIX3 protein (arrow).
TA330271 - SIX3
WB Suggested Anti-SIX3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate
TA342290 - SIX3
WB Suggested Anti-Six3 Antibody Titration: 0.2-1 ug/ml; Positive Control: Mouse Thymus

6 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

SIX3 antibody
  Rabbit polyclonal anti-SIX3 antibody  
Western blot analysis of extracts from A549 cells, using SIX3 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €335.00
  OriGene Technologies, Inc.

SIX3 (Center) antibody
  Rabbit polyclonal SIX3 Antibody (Center)  
SIX3 Antibody (Center) (Cat. #TA324591) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the SIX3 antibody detected the SIX3 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €415.00
  OriGene Technologies, Inc.

SIX3/6 antibody
Western blot (WB) analysis of Six3/6 antibody Cat.-No AP06651PU-N in extracts from HUVEC cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €370.00
  OriGene Technologies GmbH
+1 additional image

Lysates

Catalog No.    

SIX3 overexpression lysate
SIX3 overexpression lysate  
0.1 mg / €295.00
  OriGene Technologies, Inc.

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Six3 (GFP-tagged) - Mouse sine oculis-related homeobox 3 homolog (Drosophila) (Six3), 200 uL, >10^7 TU/mL
Lenti ORF particles, Six3 (GFP-tagged) - Mouse sine oculis-related homeobox 3 homolog (Drosophila) (Six3), 200 uL, >10^7 TU/mL  
200 µl / €930.00
  OriGene Technologies, Inc.
 

Lenti ORF particles, Six3 (Myc-DDK-tagged) - Mouse sine oculis-related homeobox 3 homolog (Drosophila) (Six3), 200 uL, >10^7 TU/mL
Lenti ORF particles, Six3 (Myc-DDK-tagged) - Mouse sine oculis-related homeobox 3 homolog (Drosophila) (Six3), 200 uL, >10^7 TU/mL  
200 µl / €830.00
  OriGene Technologies, Inc.
 

6 Item(s)

per page

Available Filters

Product Type
  1. Lysate (1)
  2. Mouse Lenti ORF Particle (2)
  3. Primary Antibody (3)
Clonality
  1. Polyclonal (3)
Target
  1. SIX3 (2)
  2. SIX3/6 (1)
Property
  1. Center (1)
Reactivity
  1. Human (Hu) (3)
  2. Mouse (Ms) (2)
  3. Rat (Rt) (2)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Enzyme Immunoassay (E) (1)
  3. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
Presentation
  1. Aff - Purified (2)
  2. Purified (1)
Host
  1. Rabbit (3)
Images
  1. 1 image (3)
Images: Applications
  1. Western blot / Immunoblot (WB) (3)
Manufacturer
  1. OriGene Technologies (6)
Service
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