Home » Target » SLC16A3 antibody

SLC16A3 antibody

Principal name

SLC16A3 antibody

Alternative names for SLC16A3 antibody

MCT3, MCT 3, MCT4, MCT 4, Monocarboxylate transporter 3, Monocarboxylate transporter 4, Solute carrier family 16 member 3

SwissProt ID

O15427 (Human), O35910 (Rat), P57787 (Mouse), P57788 (Chick)

Gene ID

9123 (SLC16A3), 80879 (Slc16a3), 80878

Ncbi ID

NP_001035887.1, NP_001035887, NM_030696, ADR83188.1, NP_001033742.1, NM_001038653, NM_030834, NM_004207, NM_001042422, NM_001042423

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P)

Background of SLC16A3 antibody

Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs),which function as proton symports and are stereoselective for L-lactate.The MCT family consists of at least eight members, MCT1-8, which contain between 10-12 transmembrane-helical (TM) domains, with the amino and carboxy termini located in the cytoplasm. MCT1 is widely expressed and is the major form of MCTs in tumor cells and erythrocytes. MCT2 is highly expressed in liver and testis, while MCT3 and MCT4 are predominantly expressed in skeletal muscle.

Western blot (WB) analysis of MCT4 antibody (Cat.-No.: AP01483PU-N) in extracts from LOVO cells.

AP01483PU-N

Western blot analysis of extracts from LOVO cells, using MOT4 Antibody. The lane on the right is treated with the synthesized peptide.

Mouse Liver; WB Suggested Anti-Slc16a3 Antibody. . Titration: 1.0 ug/ml. . Positive Control: Mouse Liver; Slc16a3 antibody - N-terminal region (ARP43796_P050) in Mouse Liver cells using Western Blot

ARP43796_P050

Western blot analysis of MCT4 expression in Jurkat (A); PC3 (B) whole cell lysates.

Western blot analysis of extracts from LOVO cells, using MOT4 antibody.The lane on the right is treated with the synthesized peptide.

TA314860

Western blot analysis of MOT4 expression in HeLa lysate

TA347939

Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: PC3 cells, hepg2 cells, Primary antibody: (SLC16A3 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes

TA351675

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using (SLC16A3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

TA351675

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using (SLC16A3 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)

TA351675

Primary Antibodies

Catalog No.	Host	Iso.	Pres.	React.	Applications
TA314860	SLC16A3 antibody
	Rabbit polyclonal anti-MOT4 antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	E, WB	0.1 ml / €335.00
						OriGene Technologies, Inc.
TA347939	SLC16A3 antibody
	Rabbit Polyclonal Anti-MOT4 Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	WB	0.1 mg / €335.00
						OriGene Technologies, Inc.
TA351675	SLC16A3 antibody
	Rabbit Polyclonal Anti-SLC16A3 Antibody
	Rabbit	IgG	Purified	Hu, Ms, Rt	E, P, WB	0.1 ml / €335.00
						OriGene Technologies, Inc.
+2 additional images
AP01483PU-N	SLC16A3 antibody
	Rabbit		Aff - Purified	Hu, Ms, Rt	WB	0.1 mg / €370.00
						OriGene Technologies GmbH

Rat Lenti ORF Particles

Catalog No.
RR213517L2V	Lenti ORF particles, Slc16a3 (GFP-tagged ORF) - Rat solute carrier family 16, member 3 (monocarboxylic acid transporter 4) (Slc16a3), 200 uL, >10^7 TU/mL
		200 µl / €1,150.00
		OriGene Technologies, Inc.

RR213517L1V	Lenti ORF particles, Slc16a3 (Myc-DDK-tagged ORF) - Rat solute carrier family 16, member 3 (monocarboxylic acid transporter 4) (Slc16a3), 200 uL, >10^7 TU/mL
		200 µl / €1,020.00
		OriGene Technologies, Inc.

Antibodies (see all»)

Kits (see all»)

Antigens

Lysates (see all»)

Tissue Slides (see all»)

Other life-science products