SNAP25 antibody
Principal name
SNAP25 antibody
Alternative names for SNAP25 antibody
SNAP-25, SUP, SNAP, Super Protein, RIC4, ric-4, Synaptosomal-associated protein 25, Synaptosomal-associated 25 kDa protein
SwissProt ID
O62414 (Caeel), P36975 (Drome), P55820 (Rabit), P60878 (Chick), P60879 (Mouse), P60880 (Human), P60881 (Rat), Q17QQ3 (Bovin), Q8IXK3 (Human), Q96FM2 (Mouse)
Ncbi ID
NP_003072.2, NP_003072, NP_505641, NP_035558, 9606, 10116, NP_112253.1, NP_570824, NM_003081, NP_035558.1, NM_011428, NM_130811, NM_030991
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Frozen Sections (C), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)
Background of SNAP25 antibody
SP-25 (or syptosomal-associated protein of 25kD) is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SRE) protein superfamily. The family includes 36 members in humans and is characterized by the SRE motif, an evolutiorily conserved stretch of 60–70 amino acids that are arranged in heptad repeats. SRE proteins are involved in exocytosis and intracellular vesicle trafficking and are essential for cell growth, hormone secretion and neurotransmission, processes that require rapid, targeted, and regulated membrane fusion. SREs can be roughly divided into vesicular (v-SREs) and target (t-SREs) based on their distribution on the transport vesicle or target membrane respectively. Thus, assembly of cogte v-/t-SREs between two opposing membranes generates trans-SRE complexes, which bring the lipid bilayers in close proximity and drive membrane fusion. SP-25, unlike most SREs, lacks a membrane-spanning region, but is attached to the cytoplasmic side of the plasma membrane by posttranslatiol modifications such as palmitoylation or farnesylation. SP-25 has been extensively studied for its role on neurol and neuroendocrine cell exocytosis where it functions as one of the plasma membrane protein t-SRE, which together with the vesicular v-SRE protein VAMP and another t-SRE such as Syntaxin 1, forms a trimeric, four-helical complex, which drives fusion of the two opposing bilayers. SP-25 is the target of several botulinum neurotoxin (BoNT) types: type A, C and E. The neurotoxins cause specific proteolytic degradation of the SP-25 protein, which in turn causes SRE complex disruption and inhibition of neurotransmitter release.
General readings
Yoshikatsu Aikawa, Mol. Biol. Cell, Feb 2006; 17: 711 - 722.
Noriko Takahashi, J. Cell Biol., Apr 2004; 165: 255 - 262.
Roy R. L. Gerona, J. Biol. Chem., Feb 2000; 275: 6328.
Yoshikatsu Aikawa, Mol. Biol. Cell, May 2006; 17: 2113 - 2124.



















































































- Quick-Filters:
- Cited (1)
- Highly Validated (8)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA502838 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI 1D5 (formerly 1D5) | |||||||
![]() |
Mouse | IgG2a | OTI 1D5 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
||||||
| TA502884 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI1D3 (formerly 1D3) | |||||||
![]() |
Mouse | IgG2a | OTI1D3 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
Highly validated antibody! |
||||||
| TA502963 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI4G5 (formerly 4G5) | |||||||
![]() |
Mouse | IgG2a | OTI4G5 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+8 additional images |
Highly validated antibody! |
||||||
| TA502965 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI 1E6 (formerly 1E6) | |||||||
![]() |
Mouse | IgG2b | OTI 1E6 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€379.00
|
| OriGene Technologies, Inc. | |||||||
+7 additional images |
Highly validated antibody! |
||||||
| TA502967 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI1G2 (formerly 1G2) | |||||||
![]() |
Mouse | IgG1 | OTI1G2 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
||||||
| TA502968 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI4B2 (formerly 4B2) | |||||||
![]() |
Mouse | IgG2a | OTI4B2 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
||||||
| TA502970 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI4B5 (formerly 4B5) | |||||||
![]() |
Mouse | IgG2a | OTI4B5 | Purified | Hu | F, ICC/IF, P, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+8 additional images |
Highly validated antibody! |
||||||
| AP06319PU-N | SNAP25 antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms, Rt | E, P, WB |
0.1 mg /
€370.00
|
||
| OriGene Technologies GmbH | |||||||
+3 additional images |
Highly validated antibody! |
||||||
| TA303020 | SNAP25 (C-term) antibody |
||||||
| Goat Polyclonal Antibody against SNAP25 | |||||||
![]() |
Goat | Aff - Purified | Can, Hu, Ms, Rt | P, WB |
0.1 mg /
€360.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA309235 | SNAP25 (C-term) antibody |
||||||
| Rabbit Anti-SNAP25 Antibody | |||||||
![]() |
Rabbit | IgG | Aff - Purified | Bov, Can, Chk, GP, Hu, Ms, non-Human Primates, Rt, Ze | WB |
0.1 ml /
€405.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA322907 | SNAP25 antibody |
||||||
| Anti-SNAP25 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
|||||||
| TA322908 | SNAP25 antibody |
||||||
| Anti-SNAP25 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
|||||||
| TA326256 | SNAP25 antibody |
||||||
| Rabbit polyclonal SNAP25 antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
|||||||
| TA326406 | SNAP25 antibody |
||||||
| Mouse monoclonal SNAP-25 Antibody | |||||||
![]() |
Mouse | IgG1 | SP-12 | Purified | Fe, Hu, Ms, Por, Rt | E, ICC/IF, WB |
0.1 mg /
€375.00
|
| OriGene Technologies, Inc. | |||||||
| TA326882 | SNAP25 antibody |
||||||
| SNAP25 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
||
| OriGene Technologies, Inc. | |||||||
+2 additional images |
|||||||
| TA328889 | SNAP25 antibody |
||||||
| Rabbit Polyclonal Anti-SNAP-25 | |||||||
![]() |
Rabbit | Purified | Hu, Ms, Rt | WB |
0.2 ml /
€585.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA347472 | SNAP25 antibody |
||||||
| Rabbit Polyclonal Anti-SNAP25 Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA502964 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI4C6 (formerly 4C6) | |||||||
![]() |
Mouse | IgG2a | OTI4C6 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
|||||||
| TA502966 | SNAP25 antibody |
||||||
| SNAP25 mouse monoclonal antibody, clone OTI4F3 (formerly 4F3) | |||||||
![]() |
Mouse | IgG2a | OTI4F3 | Purified | Hu | F, ICC/IF, WB |
0.1 ml /
€360.00
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
|||||||
| AM05336PU-N | SNAP25 antibody |
||||||
![]() |
Mouse | IgG1 | S-7B8 | Purified | Bov, Chk, Hu, Mky, Ms, Rt | P, WB |
0.1 mg /
€400.00
|
| OriGene Technologies GmbH | |||||||



















+3 additional images


















