SOX2 antibody
Principal name
SOX2 antibody
Alternative names for SOX2 antibody
Transcription factor SOX-2, ANOP3, MCOPS3, SRY-box 2, SRY-related HMG-box gene 2, SRY (sex determining region Y)-box 2
Ncbi ID
NP_003097, 9606, NP_003097.1, NP_035573.3, AAH13923, NM_003106, NM_011443
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Frozen Sections (C), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP), Dot blot (Dot)
Background of SOX2 antibody
Sox2, also known as sex determining region Y (SRY)-box 2, belongs to a diverse family of structurally-related transcription factors whose primary structure contains a 79-residue DNA-binding domain, called high mobility group (HMG) box. It plays an essential role in maintaining the pluripotency of embryonic stem cells (ESC) and determination of cell fate. Microarray analysis showed that Sox2 regulates the expression of multiple genes involved in embryonic development including FGF-4, YES1 and ZFP206. Sox2 acts as a transcriptional activator after forming a ternary complex with Oct3/4 and a conserved non-coding DNA sequence (CNS1) located approximately 2 kb upstream of the RAX promoter. The introduction of Sox2, Oct4, Myc, and Klf4, into human dermal fibroblasts isolated from a skin biopsy of a healthy research fellow was sufficient to confer a pluripotent state upon the fibroblast genome. The reprogrammed cells thus obtained resemble ESC in morphology, gene expression, and in the capacity to form teratomas in immune-deficient mice. Sox2 and other transcription factors have been introduced into cells by DNA transfection, viral infection, or microinjection. Protein transduction using TAT fusion proteins represents an alternative methodology for introducing transcription factors and other nuclear proteins into primary as well as transformed cells.
General readings
Wei Z., et al. (2009) Stem Cells. 27(12):2969-78.
Martinez-Fernandez A., et al. (2009) Circ Res. 25; 105(7):648-56.

































































- Quick-Filters:
- Cited (2)
- Highly Validated (3)
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| GT15098-100 | SOX2 antibody |
||||||
![]() |
Goat | Aff - Purified | Hu | E, ICC/IF, WB |
0.1 mg /
€460.00
|
||
| Neuromics Antibodies | |||||||
Top Selling product! |
|||||||
| TA302025 | SOX2 antibody |
||||||
| Mouse Monoclonal Antibody against SOX2 | |||||||
![]() |
Mouse | IgG1 | 57CT23.3.4 | Purified | Hu | ICC/IF, P, WB |
0.4 ml /
€415.00
|
| OriGene Technologies, Inc. | |||||||
+5 additional images |
Published recently! Highly validated antibody! |
||||||
| TA302026 | SOX2 (N-term) antibody |
||||||
| Rabbit Polyclonal Antibody against SOX2 (N-term) | |||||||
![]() |
Rabbit | Ig | Purified | Hu, Ms, Ze | F, ICC/IF, P, WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+4 additional images |
Highly validated antibody! |
||||||
| TA337182 | SOX2 antibody |
||||||
| Mouse Monoclonal SOX2 Antibody (4G8) | |||||||
![]() |
Mouse | IgG2b | 4G8 | Purified | Hu | C, P, WB |
0.1 mg /
€335.00
|
| OriGene Technologies, Inc. | |||||||
+9 additional images |
Highly validated antibody! |
||||||
| TA301462 | SOX2 antibody |
||||||
| Rabbit Polyclonal Antibody against SOX2 - Embryonic Stem Cell Marker | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Sh | F, ICC/IF, P, WB |
0.1 ml /
€475.00
|
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
|||||||
| TA306914 | SOX2 antibody |
||||||
| Rabbit Polyclonal SOX2 Antibody | |||||||
![]() |
Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, WB |
0.1 mg /
€415.00
|
|
| OriGene Technologies, Inc. | |||||||
+2 additional images |
|||||||
| TA321559 | SOX2 antibody |
||||||
| Anti-SOX2 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
|||||||
| TA321560 | SOX2 antibody |
||||||
| Anti-SOX2 Rabbit Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+1 additional image |
|||||||
| TA327960 | SOX2 antibody |
||||||
| Rabbit Polyclonal anti-SOX2 (NH2 terminus) Antibody | |||||||
![]() |
Rabbit | IgG | Poly6308 | Purified | Hu | ICC/IF, WB |
0.2 ml /
€300.00
|
| OriGene Technologies, Inc. | |||||||
| TA332386 | SOX2 antibody |
||||||
| Rabbit anti-SOX2 Polyclonal Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA336549 | SOX2 antibody |
||||||
| Rabbit Polyclonal SOX2 Antibody | |||||||
![]() |
Rabbit | Purified | Fi, Hu, Ms, Rt | C, E, WB |
0.1 mg /
€395.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA336966 | SOX2 antibody |
||||||
| Rabbit Polyclonal SOX2 Antibody | |||||||
![]() |
Rabbit | Purified | Chk, Fe, Hu, Ms, Por, Prim | P, WB |
0.1 mg /
€335.00
|
||
| OriGene Technologies, Inc. | |||||||
+1 additional image |
|||||||
| TA347056 | SOX2 antibody |
||||||
| Mouse Monoclonal Sox2 Antibody | |||||||
![]() |
Mouse | IgG1 | 2A10-F11-F12 | Purified | ICC/IF, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
+3 additional images |
|||||||
| TA351628 | SOX2 antibody |
||||||
| Rabbit Polyclonal Anti-SOX2 Antibody | |||||||
![]() |
Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| AM06273SU-N | SOX2 antibody |
||||||
![]() |
Mouse | IgG1 | 10F10C9 | Ascites | Hu | WB |
0.1 ml /
€340.00
|
| OriGene Technologies GmbH | |||||||
| AM06557SU-N | SOX2 antibody |
||||||
![]() |
Mouse | IgG1 | 10F10 | Ascites | Hu | E, ICC/IF, P, WB |
0.1 ml /
€380.00
|
| OriGene Technologies GmbH | |||||||
+2 additional images |
|||||||
| AP08354PU-N | SOX2 (N-term) antibody |
||||||
![]() |
Rabbit | IgG | Aff - Purified | Hu | P, WB |
50 µl /
€425.00
|
|
| OriGene Technologies GmbH | |||||||
| AP11922PU-N | SOX2 antibody |
||||||
![]() |
Rabbit | Ig | Purified | Hu | WB |
0.4 ml /
€415.00
|
|
| OriGene Technologies GmbH | |||||||
| AP26065PU-N | SOX2 (76-80) antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | WB |
0.1 mg /
€300.00
|
||
| OriGene Technologies GmbH | |||||||
| AP26065PU-S | SOX2 (76-80) antibody |
||||||
![]() |
Rabbit | Aff - Purified | Hu, Ms | WB |
50 µg /
€230.00
|
||
| OriGene Technologies GmbH | |||||||

















































+5 additional images
![Western Blot: SOX2 Antibody (4G8) [TA337182] - Western blot detection of SOX2 in A. HEK293 cell lysate B. NCCIT cell lysate and C. Full length recombinant protein.](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NBP2-29623-1-W.jpg)






![Western Blot: SOX2 Antibody [TA336549] - WB analysis of SOX-2 protein in 10ug of normal human brain lysate with SOX-2 antibody TA336549 at a dilution of 1:500](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NB110-79875-1-W.jpg)
![Western Blot: SOX2 Antibody [TA336966] - analysis of SOX2 in mouse embryo brain lysate in the 1) absence and 2) presence of immunizing peptide using this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used fo](https://m1.acris-antibodies.com/catalog/product/cache/1/small_image/50x50/9df78eab33525d08d6e5fb8d27136e95/OriGene/NBP2-24390-1-W.jpg)






