SSTR2 antibody
Principal name
SSTR2 antibody
Alternative names for SSTR2 antibody
Somatostatin receptor type 2, SS-2-R, SS2-R, SS2R, SRIF-1
SwissProt ID
O14470 (Schpo), P30680 (Rat), P30874 (Human), P30875 (Mouse), P34993 (Bovin), P34994 (Pig), Q49LX6 (Canfa)
Ncbi ID
NP_001041, 9606, 10116, NP_001041.1, NM_001050, NP_062221.1, NP_001036071.1, NM_001042606, NM_009217, NM_019348
Available reactivities
Available hosts
Available applications
Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Frozen Sections (C), Flow Cytometry (F), Immunoprecipitation (IP), Paraffin Sections (P)
Background of SSTR2 antibody
Somatostatin is a small cyclic peptide that is widely expressed throughout the central nervous system and peripheral tissues. In peripheral tissues, somatostatin exerts inhibitory effects on secretion processes, whereas in the brain, it acts as a neurotransmitter in both a stimulatory and an inhibitory manner. Somatostatin mediates its action via six high affinity G-protein-coupled receptors (SSTR1, SSTR2a, SSTR2b, SSTR3, SSTR4, and SSTR5), which are encoded by five genes. Expression of the different receptors is developmentally regulated in a time- and tissue-specific manner. Somatostatin receptors have been found on a variety of neuroendocrine tumors, such as paragangliomas, carcinoids, and breast tumors. Synthetic peptide derivatives of somatostatin have been successfully used in the treatment of neuroendocrine maligncies and in vivo imaging of tumors that are positive to somatostatin receptors. In general, SSTR2 is the most common SSTR subtype found in human tumors, followed by SSTR1, with SSTR3 and SSTR4 being less common.
Human Muscle; WB Suggested Anti-SSTR2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Human Muscle; SSTR2 antibody - middle region (ARP59561_P050) in Human Muscle cells using Western Blot
Western blot analysis of SSTR2 expression in THP1 (A); NIH3T3 (B); H9C2 (C) whole cell lysates.
ELISA: Somatostatin Receptor 2 Antibody
Immunohistochemistry: Somatostatin Receptor 2 Antibody - Staining of rat tissue paraffin embedded.
Predicted band size: 41 kDa . Positive control: Mouse thymus tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug per lane Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
Predicted cell location: Cytoplasm. Positive control: Human ovarian cancer tissue . Recommended dilution: 1/50-200 The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using SSTR2 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification:x200)
Predicted band size: 41 kDa . Positive control: Mouse thymus tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 60 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute)
Western blot analysis of rat brain membranes: 1. Anti-Somatostatin Receptor Type 2 antibody , (1:400). 2. Anti-Somatostatin Receptor Type 2 antibody, preincubated with the control peptide antigen.
Western blot analysis of rat brain (lanes 1 and 3) and rat pancreas (lanes 2 and 4) lysates: 1. Anti-Somatostatin Receptor Type 2 (extracellular) antibody, (1:200). 2. Anti-Somatostatin Receptor Type 2 (extracellular) antibody, preincubated with the control peptide antigen.
IHC staining of rat hippocampus using Anti-Somatostatin Receptor Type 2 (extracellular) antibody. A. SSTR2 appears in neural processes (green) that are perpendicular to dentate granule layer (arrow). B. Staining of axons with mouse anti Neurofilament 200 (NF200, red). C. Confocal merge of SSTR2 and NF200 images suggests that SSTR2 is not present in axons that run through the granule layer and hilus, but rather in neuronal dendrites that ascend toward the dentate hilus (arrow).
IHC staining of mouse cortex section using Anti-SSTR2 (extracellular) antibody, (1:100). A. SSTR2 appears in neural processes (green, horizontal arrow) that are perpendicular to the cortical surface (vertical arrow). B. Staining of axons with mouse anti-Neurofilament 200 (NF200, red) appears mostly in the deep layers. C. Confocal merge of SSTR2 and NF200 images suggests that SSTR2 is in neuronal dendrites that ascend toward upper layers of cortex (vertical arrow).
Anti-SSTR2 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SSTR2 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SSTR2 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SSTR2 antibody IHC of human pancreas, islet of Langerhans. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-SSTR2 antibody IHC of human brain, subiculum neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Host: Rabbit; Target Name: SSTR2; Sample Tissue: Fetal Brain lysates; Antibody Dilution: 1.0 ug/ml
WB Suggested Anti-SSTR2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:1562500; Positive Control: Human Muscle
Primary Antibodies
| Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
|---|---|---|---|---|---|---|---|
| TA309884 | SSTR2 antibody |
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| Rabbit Polyclonal Somatostatin Receptor 2 Antibody | |||||||
 |
Rabbit | Purified | Hu, Ms, Rt | C, ICC/IF, IP, WB |
0.1 ml /
€475.00
|
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| OriGene Technologies, Inc. | |||||||
| TA321271 | SSTR2 antibody |
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| Anti-SSTR2 Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
 +1 additional image |
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| TA321272 | SSTR2 antibody |
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| Anti-SSTR2 Rabbit Polyclonal Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu, Ms, Rt | E, WB |
0.1 ml /
€335.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA329049 | SSTR2 antibody |
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| Rabbit polyclonal Anti-Somatostatin Receptor Type 2 | |||||||
 |
Rabbit | Purified | Hu, Ms, Rt | WB |
0.2 ml /
€585.00
|
||
| OriGene Technologies, Inc. | |||||||
| TA329053 | SSTR2 antibody |
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| Rabbit polyclonal Anti-Somatostatin Receptor Type 2 (extracellular) | |||||||
 |
Rabbit | Purified | Ms, Rt | WB |
0.2 ml /
€585.00
|
||
| OriGene Technologies, Inc. | |||||||
| +2 additional images |
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| TA340767 | SSTR2 (C-term) antibody |
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| Rabbit Polyclonal Anti-SSTR2 Antibody (C-Terminus) | |||||||
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Rabbit | Aff - Purified | Bear, Bov, Bt, Can, Chk, Eq, Hst, Hu, L, Ms, Por, Rt, Xen | P |
50 µg /
€425.00
|
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| OriGene Technologies, Inc. | |||||||
| TA341040 | SSTR2 antibody |
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| Rabbit Polyclonal Anti-SSTR2 Antibody (Cytoplasmic Domain) | |||||||
 |
Rabbit | Purified | Hu |
50 µg /
€425.00
|
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| OriGene Technologies, Inc. | |||||||
| TA590062 | SSTR2 antibody |
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| Rabbit Polyclonal Somatostatin Receptor 2 Antibody | |||||||
 |
Rabbit | IgG | Purified | Hu | E |
0.1 mg /
€409.00
|
|
| OriGene Technologies, Inc. | |||||||
| TA590063 | SSTR2 antibody |
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| Rabbit Polyclonal Somatostatin Receptor 2 Antibody | |||||||
|
Rabbit | IgG | Purified | Hu |
50 µg /
€409.00
|
||
| OriGene Technologies, Inc. | |||||||
| MO15109-100 | SSTR2 antibody |
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 |
Mouse | IgG | Purified | Hu, Prim | C, F, ICC/IF |
0.1 mg /
€340.00
|
|
| Neuromics Antibodies | |||||||
| RA25005-100 | SSTR2 antibody |
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 |
Rabbit | Serum | Hu, Ms, Rt | ICC/IF, WB |
0.1 ml /
€340.00
|
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| Neuromics Antibodies | |||||||
| +1 additional image |
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Proteins & Growth Factors
| Catalog No. | Species | Pres. | Purity | Source | |
|---|---|---|---|---|---|
| TP305146 | SSTR2 |
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| Recombinant protein of human somatostatin receptor 2 (SSTR2) | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€748.00
|
|
| OriGene Technologies, Inc. | |||||
Lysates
| Catalog No. | ||
|---|---|---|
| LY400438 | SSTR2 overexpression lysate |
|
|
0.1 mg /
€295.00
|
|
| OriGene Technologies, Inc. |
Rat Lenti ORF Particles
| Catalog No. | ||
|---|---|---|
| RR210159L1V | Lenti ORF particles, Sstr2 (Myc-DDK-tagged ORF) - Rat somatostatin receptor 2 (Sstr2), 200 uL, >10^7 TU/mL |
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200 µl /
€830.00
|
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| OriGene Technologies, Inc. | ||